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Investigation on Detergent Tablet Stability: from Raw Materials to Tablet Properties

  • F. Chantraine , M. Viana , N. Brielles , O. Mondain-Monval , P. Branlard , G. Rubinstenn , D. Roux and D. Chulia
Published/Copyright: May 8, 2013
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Tenside Surfactants Detergents
From the journal Tenside Surfactants Detergents Volume 43 Issue 2

Abstract

The aim of this study is to investigate the functional characteristics (mechanical strength, disintegration and dissolution) of effervescent detergent tablets with chlorine provider under various storage conditions. The contribution of surfactant to the tablet stability was studied by comparing tablets without and with surfactant. After one year of storage in polypropylene tubes, the properties were modified for both formulas but the way to reach the end-point was different. In order to precise the influence of relative humidity, the tablets were exposed to controlled humidity levels, after a preliminary drying stage: with the surfactant, stability was better at lower humidity but for higher relative humidity, tablet properties were affected to a larger extent, compared to the formula without surfactant. Raman spectroscopy pointed out modifications of effervescent couple with humidity indicating i) a beginning of effervescence in the tablets and ii) the limiting effect of the surfactant on this phenomenon.

Kurzfassung

Das Ziel dieser Studie ist die Erforschung der funktionalen Merkmale (mechanische Festigkeit, Zersetzung und Auflösung) von sprudelnden Reinigungsmittel-Tabs mit Chlorspender unter verschiedenen Konservierungsbedingungen. Der Beitrag des Tensids zur Beständigkeit der Tabs wurde erforscht, indem Tabs mit und ohne Tensid verglichen wurden. Nach einem Jahr Aufbewahrung in Polypropylen-Rohren wurden die Eigenschaften der beiden Formeln modifiziert, allerdings mit unterschiedlicher Entwicklung. Um die relative Einwirkung von Feuchtigkeit zu bestimmen, wurden die Tabs nach einer vorausgegangenen Trockenphase, kontrollierten Feuchtigkeitsstufen ausgesetzt. Die Formel mit Tensid ergab, verglichen mit der Formel ohne diesen Inhaltsstoff, dass die Stabilität bei geringerer Feuchtigkeit besser ist, aber die Eigenschaften bei einer höheren relativen Feuchtigkeit mehr beeinträchtigt sind. Die Raman Spektroskopie zeigte Modifikationen von sprudelnden Paaren mit Feuchtigkeit, die i) den Beginn des Aufbrausens in den Tabs und ii) den begrenzten Tensideinfluss dieses Phenomens anzeigt.

Keywords:: Tablet; stability; surfactant; disintegration; tensile strength
Schlüsselwörter: Tabs, Stabilität; Tensid; Zersetzung; mechanische Festigkeit
4Dr. Viana Marylène, EA 2631, Faculté de Pharmacie 2 rue du Docteur Marcland 87025 Limoges Cedex – France Tel.: +3 35 55 43 58 53 Fax: +3 35 55 43 59 10 E-mail:

Florence Chantraine is a Ph.D. student in CIFRE collaboration between the University of Limoges (GEFSOD, EA 2631, France) and the company Eurotab (Saint-Just-Saint-Rambert, France).

Dr. Marylène Viana is teaching pharmaceutical technology and biopharmaceutics at the University of Limoges (France). She is working in the research team GEFSOD EA 2631 involved in the area of divided solids.

Nelly Brielles is a Ph. D. student in CIFRE collaboration between the CNRS Unit Centre de Recherche Paul Pascal (Pessac, France) and the company Eurotab (Saint-Just-Saint-Rambert, France).

Prof. Olivier Mondain-Monval is professor at the University of Bordeaux 1. He is teaching chemistry and is working in the CNRS Unit Centre de Recherche Paul Pascal (Pessac, France) in the field of porous and hybrid colloidal materials.

Paul Branlard is a chemical engineer and senior scientist for the company Eurotab (Saint-Just-Saint-Rambert, France). He was in charge of research and development at Rhodia-Silicone (France).

Dr. Gilles Rubinstenn, PhD in chemistry and physics, is the research and development director of the company Eurotab (Saint-Just-Saint-Rambert, France).

Dr. Didier Roux is Research Director at CNRS. He was working in the CNRS Unit Centre de Recherche Paul Pascal (Pessac, France) and is now Saint Gobain Vice-President Research and Development.

Prof. Dominique Chulia is a pharmacist. She is professor of pharmaceutical technology and biopharmaceutics at the University of Limoges (France) and head of a research team (GEFSOD EA 2631) devoted to the functionalization of divided solids.

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Received: 2005-7-20
Published Online: 2013-05-08
Published in Print: 2006-04-01

© 2006, Carl Hanser Publisher, Munich

Articles in the same Issue

  1. Contents/Inhalt
  2. Contents
  3. Abstracts
  4. Abstracts
  5. Application
  6. Investigation on Detergent Tablet Stability: from Raw Materials to Tablet Properties
  7. Determination of Surfactants
  8. New Potentiometric Sensor for Determination of Low Levels of Anionic Surfactants in Industrial Effluents
  9. Novel Surfactants
  10. Polymeric Surfactants: Novel Agents with Exceptional Properties
  11. Synthesis
  12. Synthesis and Characterization of Mesoporous MCM-41 Templated by the Mixture of Cationic-Anionic Surfactant
  13. Study on Production of High-monoester Sucrose Fatty Acid Esters by Improved Metallic Salt Method and Alcoholic Separation
https://doi.org/10.3139/113.100288
Keywords for this article
Tablet; stability; surfactant; disintegration; tensile strength

Articles in the same Issue

  1. Contents/Inhalt
  2. Contents
  3. Abstracts
  4. Abstracts
  5. Application
  6. Investigation on Detergent Tablet Stability: from Raw Materials to Tablet Properties
  7. Determination of Surfactants
  8. New Potentiometric Sensor for Determination of Low Levels of Anionic Surfactants in Industrial Effluents
  9. Novel Surfactants
  10. Polymeric Surfactants: Novel Agents with Exceptional Properties
  11. Synthesis
  12. Synthesis and Characterization of Mesoporous MCM-41 Templated by the Mixture of Cationic-Anionic Surfactant
  13. Study on Production of High-monoester Sucrose Fatty Acid Esters by Improved Metallic Salt Method and Alcoholic Separation
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