Startseite Effect of Maltodextrin and Temperature on Micellar Behavior of Bile Salts in Aqueous Medium: Conductometric and Spectrofluorimetric Studies
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Effect of Maltodextrin and Temperature on Micellar Behavior of Bile Salts in Aqueous Medium: Conductometric and Spectrofluorimetric Studies

  • Suvarcha Chauhan EMAIL logo , Vivek Sharma , Kuldeep Singh und M.S. Chauhan
Veröffentlicht/Copyright: 5. Dezember 2018

Abstract

Conductivity and fluorescence probe techniques have been employed to study the micellar behavior of bile salts i.e. sodium cholate (1–20 mmol⋅kg−1) and sodium deoxycholate (0.5–10.0 mmol⋅kg−1) in aqueous solutions of maltodextrin (0.0, 0.5, 1.1, and 1.6 mmol⋅kg−1) at different temperatures. The influence of maltodextrin on the micellization behavior of bile salts has been determined in terms of critical micelle concentration (CMC) values obtained from conductivity measurement. The variation in CMC values has been discussed by considering the alteration in the hydrophobic environment of maltodextrin-sodium cholate/sodium deoxycholate complex imparted by the carbohydrate molecules. In order to substantiate the CMC values determined from conductivity method, the fluorescence probe study of aqueous sodium cholate and sodium deoxycholate solutions in presence of fluorescent, pyrene has also been carried. The CMC values obtained from both techniques are in full agreement with each other. Moreover, application of charged pseudo-phase separation model has been made to discuss the thermodynamics of the system.

Acknowledgments

Vivek Sharma and Kuldeep Singh thank Himachal Pradesh University, Shimla for the award of Junior Research Fellowship (F.No. 1-3/2013-HPU (DS) 5111 and No.1-3/2016-HPU(DS), respectively). Financial support from UGC-SAP (DRS-I) (No. F.540/3/DRS/2010 (SAP-1)) to Department of Chemistry, HPU is also acknowledged.

  1. Conflict of interest: The authors declare no competing financial interest.

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Supplementary Material

The online version of this article offers supplementary material (https://doi.org/10.1515/zpch-2017-1060).


Received: 2017-10-18
Accepted: 2018-11-16
Published Online: 2018-12-05
Published in Print: 2019-08-27

©2019 Walter de Gruyter GmbH, Berlin/Boston

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