Elaeocarpus floribundus Bl. seeds as a new source of bioactive compounds with promising antioxidant and antimicrobial properties
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Ayorinde V. Ogundele
Abstract
The fruits of Elaeocarpus floribundus Bl. (Elaeocarpaceae) are edible and are normally prescribed for treatment of diseases. The medicinal uses of the fruit create considerable quantities of seeds as wastes. In an attempt to valorise this biomass, we studied the antimicrobial and antioxidant activities of the ethanolic seed extract. The extract inhibited the growth of the tested pathogens and was also a very strong scavenger of DPPH free radicals. Consequently, the extract was phytochemically investigated and this study reports the initial isolation of five phenolic compounds from this source. The structures of the isolated compounds were elucidated by spectra analyses including HR-ESI-MS, 1D and 2D NMR experiments. The isolated compounds exhibited a wide range of antimicrobial activities against the tested pathogens. Gallic acid (4) showed the most activity against Bacillus subtilis with a minimum inhibitory concentration (MIC) value of 30 µg/mL, while the MIC values of the antimicrobial standards range between 10 and 35 µg/mL. Compound 4, crude ethanolic extract, and the ethyl acetate fraction were more a potent free radical scavenger of DPPH compared to ascorbic acid. Hence, the seeds of E. floribundus could be considered as a new source of bioactive compounds for pharmaceutical and food-related industries.
Funding source: CSIR-TWAS FELLOWSHIP
Award Identifier / Grant number: FR number: 3240287339
Acknowledgments
We thank the Director of CSIR-NEIST, for providing the required facilities for this work. A.V.O gracefully appreciates CSIR-TWAS for the Postgraduate Fellowship award (FR number: 3240287339) and AcSIR, New Delhi for PhD registration.
Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: We would like to thank the CSIR-TWAS for financial support.
Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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Supplementary material
The online version of this article offers supplementary material (https://doi.org/10.1515/znc-2020-0114).
© 2020 Walter de Gruyter GmbH, Berlin/Boston
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Articles in the same Issue
- Frontmatter
- Review Article
- A systematic review of botany, phytochemicals and pharmacological properties of “Hoja santa” (Piper auritum Kunth)
- Research Articles
- Inhibition of chikusetsusaponin IVa on inflammatory responses in RAW264.7 cell line via MAPK pathway
- Potential insecticidal activity of aminonaphthoquinone Mannich bases derived from lawsone and their copper (II) complex derivatives
- Design and synthesis of novel n-butyphthalide derivatives as promising botanical fungicides
- Cotinus coggygria Scop. induces cell cycle arrest, apoptosis, genotoxic effects, thermodynamic and epigenetic events in MCF7 breast cancer cells
- Elaeocarpus floribundus Bl. seeds as a new source of bioactive compounds with promising antioxidant and antimicrobial properties
- Structural elucidation and neuroprotective activities of lignans from the flower buds of Magnolia biondii Pamp.
- Distillation time effecting on the composition of Origanum floribundum essential oils and their antioxidant and antimicrobial activities
- Root essential oil of Chrysopogon zizanioides relaxes rat isolated thoracic aorta – an ex vivo approach
- Synergistic antibacterial combination of Lavandula latifolia Medik. essential oil with camphor
