Alcohol-induced behavior change in zebrafish models
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David J. Echevarria
Abstract
Zebrafish are at the forefront of neurobiological research and have been gaining popularity as a viable and valid behavioral model in a variety of research applications (e.g., assessing drug induced behavioral changes). This model becomes even more attractive when considering the behavioral changes that follow exposure to compounds that are water-soluble. As such, several studies have implicated both acute and chronic ethanol exposure in the modulation of zebrafish behavior. Within this arena there appears to be a common trend across multiple studies. As with many drugs ethanol appears to influence behavior in a dose-dependent manner. In this review, we compare and contrast several studies that measure behavior as a result of alcohol exposure. Appended to this review are pilot data that report zebrafish blood alcohol concentrations as a function of acute exposure.
©2011 by Walter de Gruyter Berlin New York
Articles in the same Issue
- Publisher's Note
- A new start for Reviews in the Neurosciences
- Guest Editorial
- A small fish with a big future: zebrafish in behavioral neuroscience
- Application of zebrafish oculomotor behavior to model human disorders
- Shoaling in zebrafish: what we don’t know
- Sleep and its regulation in zebrafish
- Zebrafish behavioural assays of translational relevance for the study of psychiatric disease
- Stressing zebrafish for behavioral genetics
- Imaging escape and avoidance behavior in zebrafish larvae
- Zebrafish assessment of cognitive improvement and anxiolysis: filling the gap between in vitro and rodent models for drug development
- Alcohol-induced behavior change in zebrafish models
- Zebrafish models to study drug abuse-related phenotypes
- The role of dopaminergic signalling during larval zebrafish brain development: a tool for investigating the developmental basis of neuropsychiatric disorders
- Let there be light: zebrafish neurobiology and the optogenetic revolution
Articles in the same Issue
- Publisher's Note
- A new start for Reviews in the Neurosciences
- Guest Editorial
- A small fish with a big future: zebrafish in behavioral neuroscience
- Application of zebrafish oculomotor behavior to model human disorders
- Shoaling in zebrafish: what we don’t know
- Sleep and its regulation in zebrafish
- Zebrafish behavioural assays of translational relevance for the study of psychiatric disease
- Stressing zebrafish for behavioral genetics
- Imaging escape and avoidance behavior in zebrafish larvae
- Zebrafish assessment of cognitive improvement and anxiolysis: filling the gap between in vitro and rodent models for drug development
- Alcohol-induced behavior change in zebrafish models
- Zebrafish models to study drug abuse-related phenotypes
- The role of dopaminergic signalling during larval zebrafish brain development: a tool for investigating the developmental basis of neuropsychiatric disorders
- Let there be light: zebrafish neurobiology and the optogenetic revolution
