Non-responsive Dihydropteridine Reductase Deficiency

Articles in the same Issue

1. Pterins, Folates and Biogenic Amines in Neurology, Pediatrics and Immunology: Preface
2. Molecular Basis for the Phenotypic Diversity of Phenylketonuria
3. Molecular Basis of Phenylketonuria in Italy
4. Monitoring Treatment in Tetrahydrobiopterin Deficiency
5. Prenatal Diagnosis of Tetrahydrobiopterin (BH4) Synthase Deficiency
6. Prenatal Diagnosis of Dihydropteridine Reductase Deficiency in a Twin Pregnancy
7. Non-responsive Dihydropteridine Reductase Deficiency
8. 7-Substituted Pterins: Loading Experiments with 3'-Mono Deuterated Tetrahydro-L-Biopterin
9. 7-Substituted Pterins: Formation in Carbinolamine Dehydratase Deficiency
10. Primapterinuria: A Clinical Update
11. Fetal Guinea-Pig Model for Tetrahydrobiopterin Deficiency
12. Intravenous Infusion of High Dose Methotrexate, Metabolism of Pteridines and Consequences for the Tetrahydrobiopterin Dependent Hydroxylases
13. Cloning and Sequencing of cDNA Encoding Human Sepiapterin Reductase
14. 6-Pyruvoyl Tetrahydropterin Synthase in Human Tissues and Cell Lines
15. Stereostructure and Reactivity of 6-Pyruvoyl Tetrahydropterin Molecule Estimated by Molecular-Orbital Method
16. Current Knowledge on Pteridine Dependence of Nitric Oxide Synthase
17. (6R)-5,6,7,8-Tetrahydro-L-Biopterin-Dependent Activation of Soluble Guanylate Cyclase in the Rat Cerebellum is Mediated by Nitric Oxide Formation
18. Tetrahydrobiopterin-Dependent Conversion of L-Arginine to L-Citrulline and Nitric Oxide in Murine and Human Cells
19. Human Liver Pterin 4 a-Carbinolamine Dehydratase. Purification and Characterization
20. Biochemical and Immunological Characterization of Rat and Human Phenylalanine Hydroxylase
21. Tryptophan Hydroxylase and Protein Kinase Interactions; Does Phosphorylation Cause Activation?
22. Molecular Mechanisms of Tetrahydrobiopterin Action on Neurotransmitter Release
23. Age-Related Changes in Brain 6R-L-erythro-5,6,7,8-Tetrahydrobiopterin (R-THBP) and Biogenic Amine Levels in Fischer-344 Rats
24. Effect of Nerve Growth Factor and Dibutyryl Cyclic AMP on Biopterin and Catecholamine Levels of PC12h Pheochromocytoma Cells
25. Relationship between Seasonal Colour Dimorphism and Pteridines in the Scorpion Fly, Panorpa japonica, Thunberg
26. Effects of Environmental Conditions on Urinary Biopterin and Catecholamines in Rats
27. Reduced Pterins of the Retina in Response to Light Exposure
28. Identification of Pterin Binding Sites on Class I HLA Molecules Associated with the Interleukin 2 Receptor
29. Biopterin and Neopterin Serum Levels in Trypanosoma-infected dogs
30. Mechanism of Interferon Induction and Pteridine Production in HIV Infection
31. Cytokines and Viral Gene Products as Regulators of Pterin Synthesis in Cells of the Immune System
32. New Pteridine Assay System Using Automated Sequential Trace Enrichment of Dialysates
33. Biopterin and Neopterin in Various Milks and Infant Formulas
34. Pterin Chemistry, Part 91. Synthesis and Crystal Structure of the First Molybdenum (IV)-q-dihydro-L-Biopterin Complex
35. Glyceryl Etherase [EC 1.14.16.5] from Rat Liver: A Convenient Assay for Structure-Activity Relationship Studies
36. A New Scalable Route to Resolving the α-Monoesters of dl 5-Formyl 5,6,7,8-Tetrahydropteroylmono-L-Glutamic Acid
37. Synthesis and Properties of N-(α-Aminoacyl) Derivatives of Methotrexate
38. ¹³C-Labelled Folates as NMR Probes of the Binding of Folate to Bacterial Dihydrofolate Reductases
39. Isomer Distributions and Separation of 6- and 7- Methyl-8-Alkyl Pterins
40. NMR Studies of the Structures and Degradation of 8-(2’-Hydroxyethyl)Pterins
41. Progress on the Unambiguous Synthesis of S-Methyl-7,8-dihydropterin
42. Use of SCX HPLC in the Study of 8-Alkyl-Pterins and their Reduced Derivatives
43. Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate
44. Interactions of Methotrexate, Trimetrexate and Piritrexim with Human and L. casei Dihydrofolate Reductases — Steady State Inhibition Constants and Dissociation Rates
45. Activation of Methotrexate Prodrugs by Enzyme/Monoclonal Antibody Conjugates
46. New Insights into the Roles of Critical Residues in the Active Site of Thymidylate Synthase: Results from Site-Directed Mutagenesis Interpreted in Light of a “High- Resolution” Kinetic Mechanism for Wild-Type Enzyme
47. Affinity Purification of Folate Transport Proteins Using Biotin Derivatives of Methotrexate and Folate
48. Inhibition of Amido Phosphoribosyltransferase by Antifolates in Mouse L1210 Leukaemia Cells
49. The Function of the Active Site Glutamate in Human Dihydrofolate Reductase
50. Prediction of Relative Binding Constants of Cofactors and Designed Ligands to Dihydrofolate Reductase by Computer Simulation
51. Biochemical Effects of Folate Radiated with the Mild Energy of Far-Infrared Waves
52. Antiatherogenic Effect of Folic Acid in Alcoholism
53. Preconceptional Supplementation with Folic Acid to Prevent Recurrences and Occurences with Neural Tube Defects
54. Pharmacokinetics of High Dose Continuous Infusion (6S)-Folinic Acid in Humans
55. Measurement of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using HPLC with Coulometric Electrochemical Detection
56. Folate, Homocysteine and Monoamine Metabolism in Depression