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Biopolymer conjugation with phytochemicals and applications

  • Anchal Rana EMAIL logo , Sonal Bhardwaj and Nandita Sharma
Published/Copyright: September 6, 2023
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Physical Sciences Reviews
From the journal Physical Sciences Reviews Volume 9 Issue 8

Abstract

Sustainable and intelligent solutions are required to address the issues brought about by anthropogenic activity and the restricted availability of resources. Every nation is attempting to use each product from a natural resource in a necessary way in light of the current rise in environmental awareness. The bio-based biopolymers can be made from bacteria, animals, or plants. Biopolymers are a diverse class of compounds that are either produced by biological systems or synthesized from biological resources. Biopolymers are categorized as biodegradable and nonbiodegradable. Based on origin, they are further classified as being either bio based or fossil fuel based. Recently, biopolymers have gained immense recognition in different areas of biomedical field such as wound healing, burn dressing, tissue engineering, and fungal infection. These biodegradable polymer composites are effective at containing and releasing bioactive medications, such as probiotics, enzymes, pharmaceuticals, and nutraceuticals. Moreover, medicinal plants, a rich source of phytochemicals have been extensively used for their various therapeutic activities since ancient times and are being steadily providing the basis in modern drug delivery systems. There has been a lot of interest in the detection, separation, and use of dietary phytochemicals that may enhance human health and act as natural pigments, antioxidants, or antimicrobials well-being by preventing chronic illnesses like cancer, diabetes, obesity, and cardiovascular disorders. However, the delivery of these compounds for enhanced efficacy requires a rational approach. Therefore, the present chapter discuss about various sources of biopolymer, challenges, their construction mechanism, and their conjugation with phytochemicals as well as their applications.

Keywords: antioxidants; conjugation; enzymes; phytochemicals ; polymers ; tissue engineering
Corresponding author: Anchal Rana, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, India, E-mail:

Acknowledgments

The authors would like to thank the editors XYZ for their guidance and review of this article before its publication.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

References

1. Mills, J, White, R. Organic chemistry of museum objects. London: Butterworth-Heinemann Routledge; 2012.10.4324/9780080513355Search in Google Scholar

2. Deb, PK, Kokaz, SF, Abed, SN, Paradkar, A, Tekade, RK. Pharmaceutical and biomedical applications of polymers. In: Basic fundamentals of drug delivery. Amsterdam, NL: Elsevier; 2019:203–67 pp.10.1016/B978-0-12-817909-3.00006-6Search in Google Scholar

3. Buggy, M. Polymeric materials. In: Reference module in materials science and materials engineering. Amsterdam, NL: Elsevier; 2016.10.1016/B978-0-12-803581-8.04104-7Search in Google Scholar

4. Kaushik, K, Sharma, RB, Agarwal, S. Natural polymers and their applications. Int J Pharmaceut Sci Rev Res 2016;37:30–6.Search in Google Scholar

5. Numata, K, Kaplan, D. Biologically derived scaffolds. In: Advanced wound repair therapies. Tufts University, USA: Elsevier; 2011:524–51 pp.10.1533/9780857093301.4.524Search in Google Scholar

6. Yadav, P, Yadav, H, Shah, VG, Shah, G, Dhaka, G. Biomedical biopolymers, their origin and evolution in biomedical sciences: a systematic review. J Clin Diagn Res J Clin Diagn Res 2015;9:ZE21. https://doi.org/10.7860/JCDR/2015/13907.6565.Search in Google Scholar PubMed PubMed Central

7. Babu, RP, O’connor, K, Seeram, R. Current progress on bio-based polymers and their future trends. Progr Biomater 2013;2:8. https://doi.org/10.1186/2194-0517-2-8.Search in Google Scholar PubMed PubMed Central

8. Davidenko, N, Cameron, R, Best, S. Natural biopolymers for biomedical applications. In: Encyclopedia of biomedical engineering. Cambridge, UK: University of Cambridge; 2019:162–67 pp.10.1016/B978-0-12-801238-3.11026-8Search in Google Scholar

9. Verbeek, CJR. Products and applications of biopolymers. Croatia: InTech; 2012.10.5772/1802Search in Google Scholar

10. Anwunobi, A, Emeje, M. Recent applications of natural polymers in nanodrug delivery. J Nanomed Nanotechnol 2011;4. https://doi.org/10.4172/2157-7439. S4-002.10.4172/2157-7439.S4-002Search in Google Scholar

11. Matalanis, A, Jones, OG, McClements, DJ. Structured biopolymer-based delivery systems for encapsulation, protection, and release of lipophilic compounds. Food Hydrocoll 2011;25:1865–80. https://doi.org/10.1016/j.foodhyd.2011.04.014.Search in Google Scholar

12. Hong, S, Choi, DW, Kim, HN, Park, CG, Lee, W, Park, HH. Protein-based nanoparticles as drug delivery systems. Pharmaceutics 2020;12:1–28. https://doi.org/10.3390/pharmaceutics12070604.Search in Google Scholar PubMed PubMed Central

13. Moulton, MC, Braydich-Stolle, LK, Nadagouda, MN, Kunzelman, S, Hussaina, SM, Varma, RS. Synthesis, characterization and biocompatibility of “green” synthesized silver nanoparticles using tea polyphenols. Nanoscale 2010;2:763–70. https://doi.org/10.1039/c0nr00046a.Search in Google Scholar PubMed

14. Prameela, K, Mohan, CM, Ramakrishna, C. Biopolymers for food design: consumer-friendly natural ingredients. In: Biopolymers for food design. Amsterdam, NL: Elsevier; 2018:1–32 pp.10.1016/B978-0-12-811449-0.00001-3Search in Google Scholar

15. Li, S, Ge, Y, Li, H. Smart nanomaterials for sensor application. Sharjah, UAE: Bentham Science Publishers; 2012.10.2174/97816080524171120101Search in Google Scholar

16. Kim, SK. Marine cosmeceuticals: trends and prospects. Boca Raton, US: CRC Press; 2016.Search in Google Scholar

17. Mohan, S, Oluwafemi, OS, Kalarikkal, N, Thomas, S, Songca, SP. Biopolymerse application in nanoscience and nanotechnology. In: Recent advances in biopolymers, 107391st ed. Rijeka, UK: InTech; 2016, 66.10.5772/62225Search in Google Scholar

18. Garcia, C, Prieto, MA. Bacterial cellulose as a potential bioleather substitute for the footwear industry. Microb Biotechnol 2018;12:582–5. https://doi.org/10.1111/1751-7915.13306.Search in Google Scholar PubMed PubMed Central

19. Johnson-Green, P. Introduction to food biotechnology. Boca Raton, US: CRC Press; 2002.Search in Google Scholar

20. Harding, SE, Adams, GG, Almutairi, F, Alzahrani, Q, Erten, T, Kök, MS, Gillis, RB. Ultracentrifuge methods for the analysis of polysaccharides, glycoconjugates, and lignins. Methods Enzymol 2015;562:391–439. https://doi.org/10.1016/bs.mie.2015.06.043.Search in Google Scholar PubMed

21. Wool, R, Sun, XS. Bio-based polymers and composites, 4th ed. US: Elsevier Academic Press; 2011, 4:57 p.Search in Google Scholar

22. Pollock, V. Proteins. In: Enna, SJ, Bylund, DB, editors xPharm: The Comprehensive Pharmacology Reference. New York: Elsevier; 2007:1–11 pp.Search in Google Scholar

23. Frank-Kamenetskii, M. DNA and RNA, biophysical aspects. In: Encyclopedia of condensed matter physics. Amsterdam: Elsevier; 2005:463–72 pp.10.1016/B0-12-369401-9/00386-7Search in Google Scholar

24. SenGupta, AK. Ion exchange and solvent extraction: a series of advances, 1st ed. Boca Raton, US: CRC Press; 2007, 18.10.1201/9781420007411Search in Google Scholar

25. Maleki, A. Characterization of functional biopolymers under various external stimuli [Thesis]. Oslo: University of Oslo; 2008.Search in Google Scholar

26. Shishir, MRI, Xie, L, Sun, C, Zheng, X, Chen, W. Advances in micro and nano-encapsulation of bioactive compounds using biopolymer and lipid-based transporters. Trends Food Sci Technol 2018;78:34–60. https://doi.org/10.1016/j.tifs.2018.05.018.Search in Google Scholar

27. Vieira, MGA, da Silva, MA, dos Santos, LO, Beppu, MM. Natural-based plasticizers and biopolymer films: a review. Eur Polym J 2011;47:254–63. https://doi.org/10.1016/j.eurpolymj.2010.12.011.Search in Google Scholar

28. Reddy, N, Reddy, R, Jiang, Q. Crosslinking biopolymers for biomedical applications. Trends Biotechnol 2015;33:362–9. https://doi.org/10.1016/j.tibtech.2015.03.008.Search in Google Scholar PubMed

29. Ncube, NS, Afolayan, AJ, Okoh, AI. Assessment techniques of antimicrobial properties of natural compounds of plant origin: current methods and future trends. Afr J Biotechnol 2008;7:1797–806. https://doi.org/10.5897/ajb07.613.Search in Google Scholar

30. Dillard, CJ, German, JB. Review phytochemicals; nutraceuticals and human health. J Sci Food Agric 2000;80:1744–56. https://doi.org/10.1002/1097-0010(20000915)80:12<1744::aid-jsfa725>3.0.co;2-w.10.1002/1097-0010(20000915)80:12<1744::AID-JSFA725>3.0.CO;2-WSearch in Google Scholar

31. Packer, L, Weber, SU. The role of vitamin E in the emerging field of nutraceuticals. New York: Marcel Dekker; 2001:27–43 pp.10.1201/9780203908174.ch2Search in Google Scholar

32. Nichenametla, SN, Taruscio, TG, Barney, DL, Exon, JH. A review of the effects and mechanism of polyphenolics in cancer. Crit Rev Food Sci Nutr 2006;46:161–83. https://doi.org/10.1080/10408390591000541.Search in Google Scholar

33. Prakash, D, Gupta, C. Role of phytoestrogens as nutraceuticals in human health. Pharmacologyonline 2011;1:510–23.Search in Google Scholar

34. Kris-Etherton, P, Hecker, K, Bonanome, A, Coval, S, Binkoski, A, Hilpert, K, et al.. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 2002;113:71–88. https://doi.org/10.1016/s0002-9343(01)00995-0.Search in Google Scholar

35. Scalbert, A, Manach, C, Morand, C, Remesy, C. Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr 2005;45:287–306. https://doi.org/10.1080/1040869059096.Search in Google Scholar

36. Cieslik, E, Greda, A, Adamus, W. Contents of polyphenols in fruits and vegetables. Food Chem 2006;94:135–42. https://doi.org/10.1016/j.foodchem.2004.11.015.Search in Google Scholar

37. Wang, S, Su, R, Nie, S, Sun, M, Zhanga, J, Wu, D, et al.. Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals. J Nutr Biochem 2014;25:363–76. https://doi.org/10.1016/j.jnutbio.2013.10.002.Search in Google Scholar

38. Boon, CS, McClements, DJ, Weiss, J, Decker, EA. Factors influencing the chemical stability of carotenoids in foods. Crit Rev Food Sci Nutr 2010;50:515–32. https://doi.org/10.1080/10408390802565889.Search in Google Scholar PubMed

39. Padayachee, A, Netzel, G, Netzel, M, Day, L, Mikkelsen, D, Gidley, MJ. Lack of release of bound anthocyanins and phenolic acids from carrot plant cell walls and model composites during simulated gastric and small intestinal digestion. Food Funct 2013;4:906–16. https://doi.org/10.1039/c3fo60091b.Search in Google Scholar PubMed

40. Fang, Z, Bhandari, B. Encapsulation of polyphenols – a review. Trends Food Sci Technol 2010;21:510–23. https://doi.org/10.1016/J.TIFS.2010.08.003.Search in Google Scholar

41. Liu, F, Ma, C, McClements, DJ, Gao, Y. A comparative study of covalent and non-covalent interactions between zein and polyphenols in ethanol-water solution. Food Hydrocoll 2017;63:625–34. https://doi.org/10.1016/J.FOODHYD.2016.09.041.Search in Google Scholar

42. Flanagan, J, Singh, H. Conjugation of sodium caseinate and gum Arabic catalyzed by transglutaminase. J Agric Food Chem 2006;54:7305–10. https://doi.org/10.1021/jf061220k.Search in Google Scholar PubMed

43. Curcio, M, Puoci, F, Iemma, F, Parisi, OI, Cirillo, G, Spizzirri, UG, et al.. Covalent insertion of antioxidant molecules on chitosan by a free radical grafting procedure. J Agric Food Chem 2009;57:5933–8. https://doi.org/10.1021/jf900778u.Search in Google Scholar PubMed

44. Xie, M, Hu, B, Wang, Y, Zeng, X. Grafting of gallic acid onto chitosan enhances antioxidant activities and alters rheological properties of the copolymer. J Agric Food Chem 2014;62:9128–36. https://doi.org/10.1021/jf503207s.Search in Google Scholar PubMed

45. Pasanphan, W, Chirachanchai, S. Conjugation of gallic acid onto chitosan: an approach for green and water-based antioxidant. Carbohydr Polym 2008;72:169–77. https://doi.org/10.1016/J.CARBPOL.2007.08.002.Search in Google Scholar

46. Jakobek, L. Interactions of polyphenols with carbohydrates, lipids and proteins. Food Chem 2015;175:556–67. https://doi.org/10.1016/J.FOODCHEM.2014.12.013.Search in Google Scholar PubMed

47. Shin, SJ, Park, JY, Lee, JY, Park, H, Park, YD, Lee, KB, et al.. “On the fly” continuous generation of alginate fibers using a microfluidic device. Langmuir 2007;23:9104–8. https://doi.org/10.1021/la700818q.Search in Google Scholar PubMed

48. Zhong, Q, Jin, M. Nanoscalar structures of spray-dried zein microcapsules and in vitro release kinetics of the encapsulated lysozyme as affected by formulations. J Agric Food Chem 2009;57:3886–94. https://doi.org/10.1021/jf803951a.Search in Google Scholar PubMed

49. Zimet, P, Livney, YD. Beta-lactoglobulin and its nanocomplexes with pectin as vehicles for ω-3 polyunsaturated fatty acids. Food Hydrocoll 2009;23:1120–6. https://doi.org/10.1016/J.FOODHYD.2008.10.008.Search in Google Scholar

50. Alvim, ID, Grosso, CRF. Microparticles obtained by complex coacervation: influence of the type of reticulation and the drying process on the release of the core material. Ciência Tecnol Aliment 2010;30:1069–76. https://doi.org/10.1590/s0101-20612010000400036.Search in Google Scholar

51. Hedayati, R, Jahanshahi, M, Attar, H. Fabrication and characterization of albumin-acacia nanoparticles based on complex coacervation as potent nanocarrier. J Chem Technol Biotechnol 2012;87:1401–8. https://doi.org/10.1002/jctb.3758.Search in Google Scholar

52. Reis, CP, Neufeld, RJ, Vilela, S, Ribeiro, AJ, Veiga, F. Review and current status of emulsion/dispersion technology using an internal gelation process for the design of alginate particles. J Microencapsul 2006;23:245–57. https://doi.org/10.1080/02652040500286086.Search in Google Scholar PubMed

53. Hassan, ME, Bai, J, Dou, D. Biopolymers, definition, classification and applications. Egypt J Chem 2019;62:1725–37. https://doi.org/10.21608/ejchem.2019.6967.1580.Search in Google Scholar

54. Thankachen, RU, Nair, A, Raj, J, Areekal, NN, Udayakumar, PM, Haponiuk, JT, et al.. Biopolymers and their industrial applications, Thomas, S, Gopi, S, Amalraj, A, editors. Oxford: Elsevier; 2020:351–72 pp.Search in Google Scholar

55. Timilsena, YP, Haque, MA, Adhikari, B. Encapsulation in the food industry: a brief historical overview to recent developments. Food Nutr Sci 2020;11:481–508. https://doi.org/10.4236/fns.2020.116035.Search in Google Scholar

56. Zabot, GL, Rodrigues, FS, Ody, LP, Tres, MV, Herrera, E, Palacin, H, et al.. Encapsulation of bioactive compounds for food and agricultural applications. Polymer 2022;14:4194. https://doi.org/10.3390/polym14194194.Search in Google Scholar PubMed PubMed Central

57. Stoica, F, Condurache, NN, Aprodu, I, Andronoiu, DG, Enachi, E, Stanciuc, N, et al.. Value-added salad dressing enriched with red onion skin anthocyanins entrapped in different biopolymers. Food Chem X 2022;15. https://doi.org/10.1016/j.fochx.2022.100374.Search in Google Scholar PubMed PubMed Central

58. Song, J, Yu, Y, Chen, M, Ren, Z, Chen, L, Fu, C, et al.. Advancement of protein-and polysaccharide-based biopolymers for anthocyanin encapsulation. Front Nutr 2022;9. https://doi.org/10.3389/fnut.2022.938829.Search in Google Scholar PubMed PubMed Central

59. Sun, C, Xu, C, Mao, L, Wang, D, Yang, J, Gao, Y. Preparation, characterization and stability of curcumin-loaded zein-shellac composite colloidal particles. Food Chem 2017;228:656–67. https://doi.org/10.1016/j.foodchem.2017.02.001.Search in Google Scholar PubMed

60. Ali, EA, Nada, AA, Al-Moghazy, M. Self-stick membrane based on grafted gum Arabic as active food packaging for cheese using cinnamon extract. Int J Biol Macromol 2021;189:114–23. https://doi.org/10.1016/j.ijbiomac.2021.08.071.Search in Google Scholar PubMed

61. Mirmazloum, I, Ladányi, M, Omran, M, Papp, V, Ronkainen, VP, Pónya, Z, et al.. Co-encapsulation of probiotic Lactobacillus acidophilus and Reishi medicinal mushroom (Ganoderma lingzhi) extract in moist calcium alginate beads. Int J Biol Macromol 2021;192:461–70. https://doi.org/10.1016/j.ijbiomac.2021.09.177.Search in Google Scholar PubMed

62. Seyedabadi, MM, Rostami, H, Jafari, SM, Fathi, M. Development and characterization of chitosan-coated nanoliposomes for encapsulation of caffeine. Food Biosci 2021;40:100857. https://doi.org/10.1016/j.fbio.2020.100857.Search in Google Scholar

63. Farahani, ZK, Mousavi, M, Ardebili, SMS, Bakhoda, H. Modification of sodium alginate by octenyl succinic anhydride to fabricate beads for encapsulating Jujube extract. Curr Res Food Sci 2022;5:157–66. https://doi.org/10.1016/j.crfs.2021.11.014.Search in Google Scholar PubMed PubMed Central

64. Unsoy, G, Khodadust, R, Yalcin, S, Mutlu, P, Gunduz, U. Synthesis of Doxorubicin loaded magnetic chitosan nanoparticles for pH responsive targeted drug delivery. Eur J Pharmaceut Sci 2014;62:243–50. https://doi.org/10.1016/j.ejps.2014.05.021.Search in Google Scholar PubMed

65. Kim, ES, Lee, JS, Lee, HG. Nanoencapsulation of red ginseng extracts using chitosan with polyglutamic acid or fucoidan for improving antithrombotic activities. J Agric Food Chem 2016;64:4765–71. https://doi.org/10.1021/acs.jafc.6b00911.Search in Google Scholar PubMed

66. Kansom, T, Sajomsang, W, Saeeng, R, Charoensuksai, P, Opanasopit, P, Tonglairoum, P. Apoptosis induction and antimigratory activity of andrographolide analog (3a1)-incorporated self-assembled nanoparticles in cancer cells. AAPS PharmSciTech 2018;19:3123–33. https://doi.org/10.1208/s12249-018-1139-4.Search in Google Scholar PubMed

67. Zu, M, Ma, L, Zhang, X, Xie, D, Kang, Y, Xiao, B. Chondroitin sulfate functionalized polymeric nanoparticles for colon cancer-targeted chemotherapy. Colloids Surf B 2019;177:399–406. https://doi.org/10.1016/j.colsurfb.2019.02.031.Search in Google Scholar PubMed

68. Duse, L, Agel, MR, Pinnapireddy, SR, Schäfer, J, Selo, MA, Ehrhardt, C, et al.. Photodynamic therapy of ovarian carcinoma cells with curcuminloaded biodegradable polymeric nanoparticles. Pharmaceutics 2019;11:282. https://doi.org/10.3390/pharmaceutics11060282.Search in Google Scholar PubMed PubMed Central

69. Ribeiro, AF, Santos, JF, Mattos, RR, Barros, EGO, Nasciutti, LE, Cabral, LM, et al.. Characterization and in vitro antitumor activity of polymeric nanoparticles loaded with Uncaria tomentosa extract. An Acad Bras Cienc 2020;92:1–16. https://doi.org/10.1590/0001-3765202020190336.Search in Google Scholar PubMed

70. Mariadoss, AVA, Saravanakumar, K, Sathiyaseelan, A, Venkatachalam, K, Wang, MH. Folic acid functionalized starch encapsulated green synthesized copper oxide nanoparticles for targeted drug delivery in breast cancer therapy. Int J Biol Macromol 2020;164:2073–84. https://doi.org/10.1016/j.ijbiomac.2020.08.036.Search in Google Scholar PubMed

71. Baskararaj, S, Panneerselvam, T, Govindaraj, S, Arunachalam, S, Parasuraman, P, Pandian, SRK, et al.. Formulation and characterization of folate receptor-targeted PEGylated liposome encapsulating bioactive compounds from Kappaphycus alvarezii for cancer therapy. Biotec 2020;10:136. https://doi.org/10.1007/s13205-020-2132-7.Search in Google Scholar PubMed PubMed Central

72. Bhattacharya, S. Fabrication and characterization of chitosan based polymeric nanoparticles of Imatinib for colorectal cancer targeting application. Int J Biol Macromol 2020;151:104–15. https://doi.org/10.1016/j.ijbiomac.2020.02.151.Search in Google Scholar PubMed

73. Mariadoss, AVA, Sarvanakumar, K, Sathiyaseelan, A, Karthikkumar, V, Wang, MH. Smart drug delivery of p-Coumaric acid loaded aptamer conjugated starch nanoparticles for effective triple-negative breast cancer therapy. Int J Biol Macromol 2022;195:22–9. https://doi.org/10.1016/j.ijbiomac.2021.11.170.Search in Google Scholar PubMed

74. Pathak, N, Singh, P, Singh, PK, Sharma, S, Singh, RP, Gupta, A, et al.. Biopolymeric nanoparticles based effective delivery of bioactive compounds toward the sustainable development of anticancerous therapeutics. Front Nutr 2022. https://doi.org/10.3389/fnut.2022.963413.Search in Google Scholar PubMed PubMed Central

75. Chuah, LH, Roberts, CJ, Billa, N, Abdullah, S, Rosli, R. Cellular uptake and anticancer effects of mucoadhesive cucurmin-containing chitosan nanoparticles. Colloids Surf B Biointerfaces 2014;116:228–36. https://doi.org/10.1016/j.colsurfb.2014.01.007.Search in Google Scholar PubMed

76. Kunjiappan, S, Panneerselvam, T, Govindaraj, S, Parasuraman, P, Baskararaj, S, Sankaranarayanan, M, et al.. Design, in silico modelling and functionality theory of novel folate receptor targeted rutin encapsulated folicacid conjugated keratin nanoparticles for effective cancer treatment. Anti Cancer Agents Med Chem 2019;19:1966–82. https://doi.org/10.2174/1871520619666190702145609.Search in Google Scholar PubMed

77. Christy, EJS, Rajeshwari, A, Pius, A. Biopolymer applications in cosmeceutical industries. In: Thomas, S, Gopi, S, Amalraj, A, editors. Biopolymers and their industrial applications. Netherlands: Elsevier; 2021:219–43 pp.10.1016/B978-0-12-819240-5.00009-2Search in Google Scholar

78. Yang, S, Liu, L, Han, J, Tang, Y. Encapsulating plant ingredients for dermocosmetic application: an updated review of delivery systems and encapsulation techniques. Int J Cosmet Sci 2020;42:16–28. https://doi.org/10.1111/ics.12592.Search in Google Scholar PubMed

79. Huerta-Madronal, M, Caro-Leon, J, Espinosa -Cano, E, Aguilar, MR, Vazquez-Lasa, B. Chitosan-rosemarinic acid conjugates with anti-oxidant, anti-inflammatory and photoprotective properties. Carbohydr Polym 2021;273:118619. https://doi.org/10.1016/j.carbpol.2021.118619.Search in Google Scholar PubMed

80. Adamiak, K, Kurzawa, M, Sionkowska, A. Physicochemical performance of collagen modified by Melissa officinalis extract. Cosmetics 2021;8:95. https://doi.org/10.3390/cosmetics8040095.Search in Google Scholar

81. Riseh, RS, Skorik, YA, Thakur, VK, Pour, MM, Tamanadar, E, Noghabi, SS. Encapsulation of plant biocontrol bacteria with alginate as a main polymer material. Int J Mol Sci 2021;22:11165. https://doi.org/10.3390/ijms222011165.Search in Google Scholar PubMed PubMed Central

82. De Souza, MT, Porsani, MV, Bach, RP, De Souza, MT. Encapsulamento de Moléculas como oportunidade emergente Na agricultura. Pesqui Agropecuária Pernambucana 2021;26:1–5.10.12661/pap.2021.006Search in Google Scholar

83. do Nascimento Junior, DR, Tabernero, A, Cabral Albuquerque, ECM, Vieira de Melo, SAB. Biopesticide encapsulation using supercritical CO2: a comprehensive review and potential applications. Molecules 2021;26:4003. https://doi.org/10.3390/molecules26134003.Search in Google Scholar PubMed PubMed Central

84. Bae, M, Lewis, A, Liu, S, Arcot, Y, Lin, YT, Bernal, JS, et al.. Novel biopesticides based on nanoencapsulation of Azadirachtin with whey protein to control fall armyworm. J Agric Food Chem 2022;70:7900–10. https://doi.org/10.1021/acs.jafc.2c01558.Search in Google Scholar PubMed

85. Marcillo-Parra, V, Tupuna-Yerovi, DS, González, Z, Ruales, J. Encapsulation of bioactive compounds from fruit and vegetable by-products for food application- a review. Trends Food Sci Technol 2021;116:11–23. https://doi.org/10.1016/j.tifs.2021.07.009.Search in Google Scholar

86. Maes, C, Bouquillon, S, Fauconnier, ML. Encapsulation of essential oils for the development of biosourced pesticides with controlled release: a review. Molecules 2019;24:2539. https://doi.org/10.3390/molecules24142539.Search in Google Scholar PubMed PubMed Central

87. Taban, A, Saharkhiz, MJ, Khorram, M. Formulation and assessment of nano-encapsulated bioherbicides based on biopolymers and essential oil. Ind Crops Prod 2020;149:112348.10.1016/j.indcrop.2020.112348Search in Google Scholar

88. Karaaslan, M, Sengün, F, Cansu, U, Basyigit, B, Saglam, H, Karaaslan, A. Gum Arabic/maltodextrin microencapsulation confers peroxidation stability and antimicrobial ability to pepper seed oil. Food Chem 2021;337:127748. https://doi.org/10.1016/j.foodchem.2020.127748.Search in Google Scholar PubMed

Received: 2023-04-10
Accepted: 2023-06-23
Published Online: 2023-09-06

© 2023 Walter de Gruyter GmbH, Berlin/Boston

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  1. Frontmatter
  2. Reviews
  3. Dipeptidyl peptidase IV: a multifunctional enzyme with implications in several pathologies including cancer
  4. Structural peculiarities? Aperiodic crystals, modulated phases, composite structures
  5. Crystalline materials in art and conservation: verdigris pigments – what we know and what we still don’t know
  6. Corn starch nanocomposite films reinforced with nanocellulose
  7. Cassava starch nanocomposite films reinforced with nanocellulose
  8. Regulations for food packaging materials
  9. Process intensification using immobilized enzymes
  10. Succinic acid: applications and microbial production using organic wastes as low cost substrates
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https://doi.org/10.1515/psr-2022-0190
Keywords for this article
antioxidants; conjugation; enzymes; phytochemicals; polymers; tissue engineering

Articles in the same Issue

  1. Frontmatter
  2. Reviews
  3. Dipeptidyl peptidase IV: a multifunctional enzyme with implications in several pathologies including cancer
  4. Structural peculiarities? Aperiodic crystals, modulated phases, composite structures
  5. Crystalline materials in art and conservation: verdigris pigments – what we know and what we still don’t know
  6. Corn starch nanocomposite films reinforced with nanocellulose
  7. Cassava starch nanocomposite films reinforced with nanocellulose
  8. Regulations for food packaging materials
  9. Process intensification using immobilized enzymes
  10. Succinic acid: applications and microbial production using organic wastes as low cost substrates
  11. Microbial electrotechnology – Intensification of bioprocesses through the combination of electrochemistry and biotechnology
  12. Biopolymer conjugation with phytochemicals and applications
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