Synthesis, characterization and low energy photon attenuation studies of bone tissue substitutes
-
Shailesh Joshi
,
P.K. Ajikumar
Abstract
Epoxy composites with different weight percentages of calcium carbonate and calcium phosphate were synthesized as bone tissue substitutes (BTS) for internal dosimetry. The Fourier-transform infrared spectroscopy analysis confirmed that no chemical reaction occurred between the polymer and the fillers. Thermogravimetric analysis also showed improvement in the thermal properties of the composites due to the fillers. The uniform distribution of fillers in the epoxy matrix was established by X-ray radiography. The attenuation behavior of BTS was probed for low energy γ source 241Am (59.5 keV) using planar HPGe detector. The measured mass attenuation coefficients of BTS were found to match with the values calculated using XCOM software. The radiological properties derived for these composites were found to be on par with those of ICRU-44 cortical bone and B-100 bone equivalent plastic.
Acknowledgments
The authors would like to thank Mrs. I. Vijayalakshmi from the Radiological Safety Division, IGCAR, for the attenuation studies. The authors acknowledge Mr. N. Raghu, Mr. P. Narayana Rao and Mr. Krishna Chaitanya K. of the Quality Assurance Division, IGCAR, for their help in conducting the X-ray radiographic studies. The authors are also thankful to Mr. Ajay Rawat and Mr. S. N. Brahma of the Radiological and Environmental Safety Division, IGCAR, and Dr. Sarita Tripathi of the Fuel Chemistry Division, IGCAR, for their valuable suggestions.
References
[1] Watanabe Y, Constantinou C. In Encyclopedia of medical devices and instrumentation, John Wiley & Sons, Inc.: New York, 2006.Suche in Google Scholar
[2] Jones AK, Simon TA, Bolch WE, Holman MM, Hintenlang DE. Med. Phys. 2006, 33, 3274–3282.10.1118/1.2256687Suche in Google Scholar PubMed
[3] Pendharkar KA, Bhati S, Singh IS, Sawant PD, Sathyabama N, Nadar MY, Vijayagopal P, Patni HK, Kalyane GN, Prabhu SP, Ghare VP, Garg SP, Upgradation of internal dosimetry facilities at BARC Trombay. BARC Newsletter 2008, 296, 9–23.Suche in Google Scholar
[4] International Atomic Energy Agency (IAEA), Intercalibration of in vivo counting systems using an Asian phantom: Results of a co-ordinated research Project, 1996–1998. International Atomic Energy Agency 2003. https://www-pub.iaea.org/MTCD/Publications/PDF/te_1334_web.pdf.Suche in Google Scholar
[5] Shirotani T. J. Nucl. Sci. Technol. 1988, 25, 875–883.10.1080/18811248.1988.9735941Suche in Google Scholar
[6] Kramer GH, Hauck BM, Allen SA. Health Phys. 1998, 74, 594–601.10.1097/00004032-199805000-00007Suche in Google Scholar PubMed
[7] Kramer GH, Hauck BM. Radiat. Prot. Dosim. 2000, 88, 311–317.10.1093/oxfordjournals.rpd.a033049Suche in Google Scholar
[8] White DR. Med. Phys. 1978, 5, 467–479.10.1118/1.594456Suche in Google Scholar PubMed
[9] Constantinou C. Tissue substitutes for particulate radiations and their use in radiation dosimetry and radiotherapy, Ph.D. thesis, University of London, 1978. https://qmro.qmul.ac.uk/xmlui/handle/123456789/1718.Suche in Google Scholar
[10] Constantinou C. Br. J. Radiol. 1982, 55, 217–224.10.1259/0007-1285-55-651-217Suche in Google Scholar PubMed
[11] Joshi S, Bramhaji Rao JS, Sivasubramanian K, Kumar R, Jayaraman V, Venkatraman B. J. Polym. Res. 2017, 24:78, 1–8.Suche in Google Scholar
[12] Woodard HQ, White DR. Br. J. Radiol. 1982, 55, 277–282.10.1259/0007-1285-55-652-277Suche in Google Scholar PubMed
[13] Woodard HQ, White DR. Br. J. Radiol. 1986, 59, 1209–1219.10.1259/0007-1285-59-708-1209Suche in Google Scholar PubMed
[14] Bethesda MD. Tissue substitutes in radiation dosimetry and measurement, International Commission on Radiation Units and Measurements (ICRU) Report 44 (1989). https://icru.org/home/reports/tissue-substitutes-in-radiation-dosimetry-and-measurement-report-44.Suche in Google Scholar
[15] White DR, Martin RJ, Darlison R. Br. J. Radiol. 1977, 50, 814–821.10.1259/0007-1285-50-599-814Suche in Google Scholar PubMed
[16] Johns HE, Cunningham JR. Physics of Radiology. Charles River Media: Hingham, MA, USA, 1983.Suche in Google Scholar
[17] Jones AK, Hintenlang DE, Bolch WE. Med. Phys. 2003, 30, 2072–2081.10.1118/1.1592641Suche in Google Scholar PubMed
[18] Taylor FY. History of the Lawrence Livermore National Laboratory torso phantom, 1997. https://scholarworks.sjsu.edu/cgi/viewcontent.cgi?article=2472&context=etd_theses.Suche in Google Scholar
[19] Geske G. Radiobiologia Radiotherapia 1975, 16, 671–676.10.1016/S0040-4039(00)71951-4Suche in Google Scholar
[20] Spitz HB, Lodwick J. J. Radiat. Prot. Dosim. 2000, 89, 275–282.10.1093/oxfordjournals.rpd.a033080Suche in Google Scholar
[21] Burton B, Alexander D, Klein H, Vasquez AG, Pekarik A, Henkee C. Epoxy formulations using Jeffamine polyetheramines. Huntsman Corp.: The Woodlands, TX, 2005.Suche in Google Scholar
[22] Traub RJ, Olsen PC, Mcdonald JC. Radiat. Prot. Dosim. 2006, 121, 202–207.10.1093/rpd/nci371Suche in Google Scholar
[23] Gonzalez MG, Cabanelas JC, Baselga J. Infrared Spectroscopy – Materials Science, Engineering and Technology, IntechOpen 2012, 261. https://www.intechopen.com/books/infrared-spectroscopy-materials-science-engineering-and-technology/applications-of-ftir-on-epoxy-resins-identification-monitoring-the-curing-process-phase-separatio.10.5772/36323Suche in Google Scholar
[24] Xia MS, Yao ZT, Ge LQ, Chen T, Li HYJ. Compos. Mater. 2015, 49, 807–816.10.1177/0021998314525981Suche in Google Scholar
[25] Berzina-Cimdina L, Borodajenko N. Infrared Spectroscopy-Materials Science, Engineering and Technology. IntechOpen 2012, 123. https://www.intechopen.com/books/infrared-spectroscopy-materials-science-engineering-and-technology/research-of-calcium-phosphates-using-fourier-transformation-infrared-spectroscopy.10.5772/36942Suche in Google Scholar
[26] Murakami FS, Rodrigues PO, Campos CMTD, Silva MAS. Food Sci. Technol. 2007, 27, 658–662.10.1590/S0101-20612007000300035Suche in Google Scholar
[27] Granados-Correa F, Bonifacio-Martinez J, Serrano-Gomez J. Rev. Int. Contam. Ambie. 2010, 26, 129–134.Suche in Google Scholar
[28] Mahmoud ME, El-Khatib AM, Badawi MS, Rashad AR, El-Sharkawy RM, Thabet AA. Radiat. Phys. Chem. 2018, 145, 160–173.10.1016/j.radphyschem.2017.10.017Suche in Google Scholar
[29] Mihai R, Nicoleta S, Daniela R. Polym. Test 2001, 20, 409–417.10.1016/S0142-9418(00)00051-9Suche in Google Scholar
[30] Schneider CA, Wayne SR, Kevin WE. Nat. Methods 2012, 9, 671–675.10.1038/nmeth.2089Suche in Google Scholar PubMed PubMed Central
[31] Gwon SH, Oh JH, Kim M, Choi S, Oh KH, Sun JY. Sci. Rep. 2018, 8, 1852–1858.10.1038/s41598-018-20411-3Suche in Google Scholar PubMed PubMed Central
[32] Hosseini SH, Noushin Ezzati S, Askari M. Polym. Adv. Technol. 2015, 26, 561–568.10.1002/pat.3486Suche in Google Scholar
[33] Nambiar S, Yeow JTW. ACS Appl. Mater. Interfaces 2012, 4, 5717–5726.10.1021/am300783dSuche in Google Scholar PubMed
[34] Cherry SR, Sorenson JA, Phelps ME. Physics in Nuclear Medicine E-book, Elsevier Health Science: Philadelphia, PA, USA, 2012.10.1016/B978-1-4160-5198-5.00001-0Suche in Google Scholar
©2020 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Material properties
- Synthesis, characterization and low energy photon attenuation studies of bone tissue substitutes
- The effect of oxygen plasma pretreatment on the properties of mussel-inspired polydopamine-decorated polyurethane nanofibers
- Effects of selected bleaching agents on the functional and structural properties of orange albedo starch-based bioplastics
- Study on the thermal and structural properties of gamma-irradiated polyethylene terephthalate fibers
- Preparation and assembly
- Stereocomplex electrospun fibers from high molecular weight of poly(L-lactic acid) and poly(D-lactic acid)
- Dual-wavelength fluorescent anti-counterfeiting fibers with skin-core structure
- Graphene oxide and zinc oxide decorated chitosan nanocomposite biofilms for packaging applications
- Supramolecular adsorption of cyclodextrin/polyvinyl alcohol film for purification of organic wastewater
- Engineering and processing
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- Toward the development of polyethylene photocatalytic degradation
Artikel in diesem Heft
- Frontmatter
- Material properties
- Synthesis, characterization and low energy photon attenuation studies of bone tissue substitutes
- The effect of oxygen plasma pretreatment on the properties of mussel-inspired polydopamine-decorated polyurethane nanofibers
- Effects of selected bleaching agents on the functional and structural properties of orange albedo starch-based bioplastics
- Study on the thermal and structural properties of gamma-irradiated polyethylene terephthalate fibers
- Preparation and assembly
- Stereocomplex electrospun fibers from high molecular weight of poly(L-lactic acid) and poly(D-lactic acid)
- Dual-wavelength fluorescent anti-counterfeiting fibers with skin-core structure
- Graphene oxide and zinc oxide decorated chitosan nanocomposite biofilms for packaging applications
- Supramolecular adsorption of cyclodextrin/polyvinyl alcohol film for purification of organic wastewater
- Engineering and processing
- Effects of high-efficiency infrared heating on fiber compatibility and weldline tensile properties of injection-molded long-glass-fiber-reinforced polyamide-66 composites
- Toward the development of polyethylene photocatalytic degradation
