Home Predictive factors for preterm delivery under rural conditions in post-tsunami Banda Aceh
Article
Licensed
Unlicensed Requires Authentication

Predictive factors for preterm delivery under rural conditions in post-tsunami Banda Aceh

  • Fabienne D. Schwab EMAIL logo , Eva K. Zettler , Andala Moh , Andreas Schötzau , Uwe Gross and Andreas R. Günthert
Published/Copyright: May 14, 2015

Abstract

Objective: To assess the risk for preterm deliveries <37 week of gestation and associated prevalence of vaginal infection in a rural setting after the tsunami in Banda Aceh, Indonesia.

Methods: Wet mount microscopy, vaginal pH and vaginal swabs for microbiological culture were collected in pregnant women during the 2nd trimester from February to June of 2005 in four temporary outpatient clinics and the patients were followed up until delivery.

Results: One hundred and fifty-nine pregnant patients were screened. Sixty-two could be followed up until delivery. Thirty-nine (62.9%) delivered at term and 23 (37.1%) delivered prematurely. Significant risk factors for preterm delivery were a history of preterm delivery and group B streptococcus infection. Increased vaginal pH alone had no significant influence on preterm delivery, although there was a trend.

Conclusion: The rate of preterm delivery was high in this cohort. We suggest risk stratification for preterm delivery in rural conditions by performing a vaginal pH and wet mount microscopy. If either is suspect we suggest collecting a vaginal swab for microbiological culture for targeted treatment. Patients with a history of preterm delivery are at increased risk and should be monitored closely.


Corresponding author: Fabienne D. Schwab, Department of Obstetrics and Gynaecology, University Hospital of Basel, Basel, Switzerland, E-mail:

Acknowledgments

The German Academic Exchange Services in part supported this study. The authors thank Prof. I. Hoesli and Dr. Dorothy Huang for their critical review in the preparation of the original manuscript.

References

[1] Mendz GL, Kaakoush NO, Quinlivan JA. Bacterial aetiological agents of intra-amniotic infections and preterm birth in pregnant woman. Frontiers Cell Infect Microbiol. 2013;3:58.10.3389/fcimb.2013.00058Search in Google Scholar PubMed PubMed Central

[2] McDonald SW, Kingston D, Bayrampour H, Dolan SM, Tough SC. Cumulative psychosocial stress, coping resources, and preterm birth. Arch Womens Ment Health. 2014;17:559–68.10.1007/s00737-014-0436-5Search in Google Scholar PubMed

[3] Iams JD. Clinical practice. Prevention of preterm parturition. N Engl J Med. 2014;370:254–61.10.1056/NEJMcp1103640Search in Google Scholar PubMed

[4] Brocklehurst P, Gordon A, Heatley E, Milan SJ. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2013;1:CD000262.10.1002/14651858.CD000262.pub4Search in Google Scholar PubMed

[5] Hay PE, Lamont RF, Taylor-Robinson D, Morgan DJ, Ison C, Pearson J. Abnormal bacterial colonisation of the genital tract and subsequent preterm delivery and late miscarriage. Br Med J. 1994;308:295–8.10.1136/bmj.308.6924.295Search in Google Scholar PubMed PubMed Central

[6] Hantoushzadeh S, Sheikh M, Javadian P, Shariat M, Amini E, Abdollahi A, et al. Elevated vaginal pH in the absence of current vaginal infection, still a challenging obstetrical problem. J Matern Fetal Neonatal Med. 2014;27:582–7.10.3109/14767058.2013.823394Search in Google Scholar PubMed

[7] Zeccola P. Dividing disasters in Aceh, Indonesia: separatist conflict and tsunami, human rights and humanitarianism. Disasters. 2011;35:308–28.10.1111/j.1467-7717.2010.01213.xSearch in Google Scholar PubMed

[8] Waizenegger A, Hyndman J. Two solitudes: post-tsunami and post-conflict Aceh. Disasters. 2010;34:787–808.10.1111/j.1467-7717.2010.01169.xSearch in Google Scholar PubMed

[9] Islam A, Safdar A, Malik A. Bacterial vaginosis. J Pak Med Assoc. 2009;59:601–4.Search in Google Scholar

[10] Dunkel Schetter C. Psychological science on pregnancy: stress processes, biopsychosocial models, and emerging research issues. Annu Rev Psychol. 2011;62:531–58.10.1146/annurev.psych.031809.130727Search in Google Scholar PubMed

[11] Littleton HL, Bye K, Buck K, Amacker A. Psychosocial stress during pregnancy and perinatal outcomes: a meta-analytic review. J Psychosom Obstet Gynaecol. 2010;31:219–28.10.3109/0167482X.2010.518776Search in Google Scholar PubMed

[12] Rausch A, Gross A, Droz S, Bodmer T, Surbek D. Group B Streptococcus colonization in pregnancy: prevalence and prevention strategies of neonatal sepsis. J Perinat Med. 2009;37:124–9.10.1515/JPM.2009.020Search in Google Scholar

[13] Seyyed EZ, Toossi, Jalalvand A, Sajadi M. Group B Streptococci investigation in pre-term labors. Med Arch. 2013;67:124–5.10.5455/medarh.2013.67.124-125Search in Google Scholar

[14] Schuchat A. Epidemiology of group B streptococcal disease in the United States: shifting paradigms. Clin Microbiol Rev. 1998;11:497–513.10.1128/CMR.11.3.497Search in Google Scholar

[15] Klebanoff MA, Regan JA, Vijaya Rao A, Nugent RP, Blackwelder DA, Eschenbach JG, et al. Outcome of vaginal Infections and Prematurity Study: results of clinical trial of erythryomycin among pregnant women colonized with group B streptococci. Am J Obstet Gynecol. 1995;172: 1540–5.10.1016/0002-9378(95)90493-XSearch in Google Scholar

[16] Slager J, Lynne S. Treatment options and recommendations to reduce preterm birth in woman with short cervix. J Midwifery Womens Health. 2012;57:12–8.10.1111/j.1542-2011.2012.00210.xSearch in Google Scholar PubMed

[17] Committee on Practice Bulletins – Obstetrics, The American College of Obstetricians and Gynecologists. Practice bulletin no. 130: prediction and prevention of preterm birth. Obstet Gynecol. 2012;120:964–73.10.1097/AOG.0b013e3182723b1bSearch in Google Scholar PubMed

[18] Cybulski JS, Clements J, Prakash M. Foldscope: origami-based paper microscope. PLoS One. 2014;9:e98781.10.1371/journal.pone.0098781Search in Google Scholar PubMed PubMed Central

[19] Surbek D, Hoesli I, Holzgreve W. Morphology assessed by transvaginal ultrasonography differs in patients in preterm labor with vs. without bacterial vaginosis. Ultrasound Obstet Gynecol. 2000;15:242–5.10.1046/j.1469-0705.2000.00102.xSearch in Google Scholar PubMed

  1. The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2015-1-3
Accepted: 2015-4-17
Published Online: 2015-5-14
Published in Print: 2016-7-1

©2016 by De Gruyter

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Preventing preterm birth
  4. Original articles
  5. Vertically transmitted cytomegalovirus infection in newborn preterm infants
  6. Computerized vital signs analysis and late onset infections in extremely low gestational age infants
  7. Oral propranolol in early stages of retinopathy of prematurity
  8. Changes in incidence of iatrogenic and spontaneous preterm births over time: a population-based study
  9. Predictive factors for preterm delivery under rural conditions in post-tsunami Banda Aceh
  10. Early pregnancy serum neopterin concentrations predict spontaneous preterm birth in asymptomatic pregnant women
  11. Funisitis is more common in cervical insufficiency than in preterm labor and preterm premature rupture of membranes
  12. Amniotic fluid LPCAT1 mRNA correlates with the lamellar body count
  13. Recommendation and Guidelines for Perinatal Practice
  14. Fetal magnetic resonance imaging and ultrasound
  15. Original articles - Obstetrics
  16. Relationship between first-trimester serum placental protein-13 and maternal characteristics, placental Doppler studies and pregnancy outcome
  17. Higher D-dimer level in the early third trimester predicts the occurrence of postpartum hemorrhage
  18. Extra-abdominal removal of placenta during cesarean section: a prospective randomized controlled trial of a novel technique
  19. Correlation of intrapartum translabial ultrasound parameters with computed tomographic 3D reconstruction of the female pelvis
  20. Cost effectiveness of universal umbilical cord blood gas and lactate analysis in a tertiary level maternity unit
  21. Original articles - Fetus
  22. Is there a sex difference in fetal behavior? A comparison of the KANET test between male and female fetuses
  23. Determination of antepartum and intrapartum risk factors associated with neonatal intensive care unit admission
  24. Short communication
  25. A guide on how to build a novel home-made part task training simulator for cervical cerclage training
  26. Congress Calendar
  27. Congress Calendar
Downloaded on 29.11.2025 from https://www.degruyterbrill.com/document/doi/10.1515/jpm-2015-0004/html
Scroll to top button