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Laparoscopic adrenalectomy in children with diverse adrenal pathologies: the impact of pre-operative imaging in decision making process

  • Dragan Kravarusic , Osher Cohen , Zaki Elias Assi , Boaz Markel , Osnat Konen , Orly Rafael and Yael Dreznik ORCID logo EMAIL logo
Published/Copyright: January 1, 2025

Abstract

Objectives

The aim of this study was to assess the impact of pre-operative imaging regarding selecting cases of children’s who underwent laparoscopic adrenalectomy due to adrenal masses in two tertiary medical centers.

Methods

We performed a retrospective review of all laparoscopic adrenalectomy performed at two tertiary medical centers in Israel between 2017 and 2023.

Results

Sixteen (n=16) patients, 10 girls and six boys, underwent laparoscopic adrenalectomy through a transperitoneal approach. The median age was 10 years (range: eight months to 17.3 years). Six masses were incidentalomas. Preoperative imaging (ultrasonography, CT, and MRI) demonstrated a mass in the right adrenal (n=9) and left adrenal (n=7), with tumor sizes ranging from 1.8 to 5.3 cm in maximum diameter. Operative results showed minimal blood loss and no conversions to laparotomy. There were no postoperative complications. Pathological diagnoses included neuroblastoma (n=8), cortical hormone-secreting tumors (n=3), pheochromocytoma (n=2), adrenal cortical adenoma (n=2), and adrenal metastatic Ewing sarcoma (n=1). Eleven masses were defined as benign and five as malignant tumors.

Conclusions

Laparoscopic adrenalectomy appears to be a safe and effective technique in selected cases with adrenal masses. Among our cohort, malignant masses were more common compared to the predominantly benign adrenal masses seen in adults. Vascular encasement was a major factor in determining the feasibility of the laparoscopic approach, with preoperative imaging playing a critical role in this assessment.


Corresponding author: Dr. Yael Dreznik MD, Department of Pediatric and Adolescent Surgery, Schneider Children’s Medical Center of Israel, Petah-Tiqwa, Israel, Affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 14 Kaplan St, Tel-Aviv, Israel, E-mail:

  1. Research ethics: The study was conducted in accordance with the Declaration of Helsinki (RMC/2023).

  2. Informed consent: Not applicable.

  3. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  4. Use of Large Language Models, AI and Machine Learning Tools: None declared.

  5. Conflict of interest: The authors state no conflict of interest.

  6. Research funding: None declared.

  7. Data availability: Not applicable.

References

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Received: 2024-10-15
Accepted: 2024-12-11
Published Online: 2025-01-01
Published in Print: 2025-02-25

© 2024 Walter de Gruyter GmbH, Berlin/Boston

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