The beneficial effect of psychological support on mothers with PKU children who suffer from social discrimination and damage of quality of life
-
Kostas Konstantinos Iakovou
and
Kleopatra Schulpis
Abstract
Background
Phenylketonuria (PKU) is a metabolic disorder of phenylalanine (phe) metabolism caused by the liver enzyme phe hydroxylase deficiency resulting in mental retardation. The only treatment for this disorder is the lifelong restriction of natural protein supplemented with phe-free amino acid formula. The aim of this study was to demonstrate the beneficial effect of psychological support in relation to the educational status on mothers with PKU children, who suffered from social discrimination (SD) and damage of quality of life (QLD).
Methods
A total number of 42 mothers with PKU children with a mean age of 26.8 years took part in this study. According to their educational status, they were divided into three groups: group a, primary school (n = 13); group b, high school (n = 15) and group c, university degree (n = 14). Psychological support was given once per week for 1 year.
Results
University degree mothers achieved the best results in ameliorating their symptoms and signs. Mothers who had completed high school felt a moderate amelioration of their SD and QL, whereas those who had finished primary school only felt a mild reduction of their symptoms. Educational status of the affected mothers should be always taken into account for the classification of the affected mothers into therapeutic groups. Familial and professional environment are very important for the success of psychological support.
Conclusions
Overall, the psychological support related to symptoms and signs of this metabolic disorder is in comparison with that in diabetic patients.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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©2020 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Editorial
- Inborn errors of metabolism
- Reviews
- Nutrition and medical support during pregnancy and lactation in women with inborn errors of intermediary metabolism disorders (IEMDs)
- The association between prenatal exposure to organochlorine compounds and neonatal thyroid hormone levels: a systematic review
- Original Articles
- Investigating the incidence rate and geographical distribution of congenital hypothyroidism among neonates in Isfahan province using geographic information system (GIS) between 2002 and 2015
- Analysis of five cases of hypermethioninemia diagnosed by neonatal screening
- What is the evidence for beneficial effects of growth hormone treatment beyond height in short children born small for gestational age? A review of published literature
- Machine learning-based prediction of response to growth hormone treatment in Turner syndrome: the LG Growth Study
- Pathogenic/likely pathogenic variants in the SHOX, GHR and IGFALS genes among Indian children with idiopathic short stature
- Celiac disease in Saudi children with isolated short stature: is it rare or are we not screening rigorously enough?
- The beneficial effect of psychological support on mothers with PKU children who suffer from social discrimination and damage of quality of life
- Long-term effects of GnRH agonist treatment on body mass index in girls with idiopathic central precocious puberty
- Sudden sex hormone withdrawal and the effects on body composition in late pubertal adolescents with gender dysphoria
- The alteration of IGF-1 levels and relationship between IGF-1 levels and growth velocity during GnRH analogue therapy
- BMI relationship to the onset of puberty: assessment of growth parameters and sexual maturity changes in Egyptian children and adolescents of both sexes
- The effects of a 12-week jump rope exercise program on body composition, insulin sensitivity, and academic self-efficacy in obese adolescent girls
- Onset of pituitary hormone deficiencies in optic nerve hypoplasia: a temporal trend analysis of 32 children at Mayo Clinic
- Dietary practices in methylmalonic acidaemia: a European survey
- Case Reports
- Clinical findings in five Turkish patients with citrin deficiency and identification of a novel mutation on SLC25A13
- A rare case of primary coenzyme Q10 deficiency due to COQ9 mutation
- Sinusitis, an under-reported adverse effect in children treated with radioactive iodine therapy and review of the current literature
- Acknowledgment
Articles in the same Issue
- Frontmatter
- Editorial
- Inborn errors of metabolism
- Reviews
- Nutrition and medical support during pregnancy and lactation in women with inborn errors of intermediary metabolism disorders (IEMDs)
- The association between prenatal exposure to organochlorine compounds and neonatal thyroid hormone levels: a systematic review
- Original Articles
- Investigating the incidence rate and geographical distribution of congenital hypothyroidism among neonates in Isfahan province using geographic information system (GIS) between 2002 and 2015
- Analysis of five cases of hypermethioninemia diagnosed by neonatal screening
- What is the evidence for beneficial effects of growth hormone treatment beyond height in short children born small for gestational age? A review of published literature
- Machine learning-based prediction of response to growth hormone treatment in Turner syndrome: the LG Growth Study
- Pathogenic/likely pathogenic variants in the SHOX, GHR and IGFALS genes among Indian children with idiopathic short stature
- Celiac disease in Saudi children with isolated short stature: is it rare or are we not screening rigorously enough?
- The beneficial effect of psychological support on mothers with PKU children who suffer from social discrimination and damage of quality of life
- Long-term effects of GnRH agonist treatment on body mass index in girls with idiopathic central precocious puberty
- Sudden sex hormone withdrawal and the effects on body composition in late pubertal adolescents with gender dysphoria
- The alteration of IGF-1 levels and relationship between IGF-1 levels and growth velocity during GnRH analogue therapy
- BMI relationship to the onset of puberty: assessment of growth parameters and sexual maturity changes in Egyptian children and adolescents of both sexes
- The effects of a 12-week jump rope exercise program on body composition, insulin sensitivity, and academic self-efficacy in obese adolescent girls
- Onset of pituitary hormone deficiencies in optic nerve hypoplasia: a temporal trend analysis of 32 children at Mayo Clinic
- Dietary practices in methylmalonic acidaemia: a European survey
- Case Reports
- Clinical findings in five Turkish patients with citrin deficiency and identification of a novel mutation on SLC25A13
- A rare case of primary coenzyme Q10 deficiency due to COQ9 mutation
- Sinusitis, an under-reported adverse effect in children treated with radioactive iodine therapy and review of the current literature
- Acknowledgment
