Abstract
Background
Diabetes mellitus is a metabolic disorder. However, dental caries and periodontal health have not attracted much interest in diabetic patients. This study was carried out to assess the dental caries status and gingival health status in children with type 1 diabetes mellitus (T1DM).
Methods
The study group consisted of 80 children, aged 6–18 years, with T1DM. The dental caries status was recorded using the World Health Organisation (WHO) criteria. Gingival health was assessed using the Loe and Silness gingival index (GI). Data obtained were subjected to statistical analysis.
Results
The mean dental caries status for primary (decayed, extracted, filled teeth [deft]) and permanent dentition (decayed, missing, filled teeth [DMFT]) scores in diabetic children were 0.44±1.28 and 1.26±2.49, respectively. The GI scores of diabetic children were 0.33±0.48. GI in the study group significantly correlated with DMFT (p<0.001) and deft (p≤0.05).
Conclusions
Dental caries in primary dentition was lower in diabetic children but was not statistically significant, whereas dental caries in permanent dentition was significantly higher. The gingival condition of diabetic children was healthy.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: There is no funding organization that played role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. American Diabetes Association (ADA). Standards on Medical Care in Diabetes 2010. Diabetes Care 2010;33:S11–61.10.2337/dc10-S011Search in Google Scholar PubMed
2. Prasanna Kumar KM. Incidence trends for childhood type 1 diabetes in India. Indian J Endocr Metab 2015;19:34–5.10.4103/2230-8210.155378Search in Google Scholar
3. Aguiree F, Brown A, Cho NH, Dahlquist G, Dodd S, et al. IDF Diabetes Atlas, 6th ed. Brussels, Belgium: International Diabetes Federation, 2013.Search in Google Scholar
4. Ramachandran A, Snehalatha C, Abdul Khader OM, Joseph TA, Viswanathan M. Prevalence of childhood diabetes in an urban population in south India. Diabetes Res Clin Pract 1992;17: 227–31.10.1016/0168-8227(92)90098-CSearch in Google Scholar
5. Kumar P, Krishna P, Reddy SC, Gurappa M, Aravind SR, et al. Incidence of type 1 diabetes mellitus and associated complications among children and young adults: Results from Karnataka Diabetes Registry 1995–2008. J Indian Med Assoc 2008;106:708–11.Search in Google Scholar
6. Kalra S, Kalra B, Sharma A. Prevalence of type 1 diabetes mellitus in Karnal district, Haryana state, India. Diabetol Metab Syndr 2010;2:14.10.1186/1758-5996-2-14Search in Google Scholar PubMed
7. Ramachandran A, Snehalatha C, Krishnaswamy CV. Incidence of IDDM in children in urban population in southern India. Madras IDDM Registry Group Madras, South India. Diabetes Res Clin Pract 1996;34:79–82.10.1016/S0168-8227(96)01338-1Search in Google Scholar
8. Mohan V, Sandeep S, Deepa R, Shah B, Varghese C. Epidemiology of type 2 diabetes: Indian scenario. Indian J Med Res 2007;125:217–30.Search in Google Scholar PubMed
9. Gupta R, Misra A. Type 2 diabetes in India: regional disparities. Br J Diabetes Vasc Dis 2007;7:12–6.10.1177/14746514070070010301Search in Google Scholar
10. do Amaral FM, Ramos PG, Ferreira SR. Study on the frequency of caries and associated factors in type 1 diabetes mellitus. Arq Bras Endocrinol Metabol 2006;50:515–22.10.1590/S0004-27302006000300015Search in Google Scholar PubMed
11. Alves C, Andion J, Brandão M, Menezes R. Pathogenic aspects of the periodontal disease associated to diabetes mellitus. Arq Bras Endocrinol Metabol 2007;51:1050–7.10.1590/S0004-27302007000700005Search in Google Scholar PubMed
12. Kidambi S, Patel SB. Diabetes mellitus: considerations for dentistry. J Am Dent Assoc 2008;139(Suppl):8S–18.10.14219/jada.archive.2008.0364Search in Google Scholar PubMed
13. Lamster IB, Lalla E, Borgnakke WS, Taylor GW. The relationship between oral health and diabetes mellitus. J Am Dent Assoc 2008;139(Suppl):19S–24.10.14219/jada.archive.2008.0363Search in Google Scholar PubMed
14. Iughetti L, Marino R, Bertolani MF, Bernasconi S. Oral health in children and adolescents with IDDM – a review. J Pediatr Endocrinol Metab 1999;12(5 Suppl 2):603–10.10.1515/JPEM.1999.12.5.603Search in Google Scholar
15. Twetman S, Johansson I, Birkhed D, Nederfors T. Caries incidence in young type 1 diabetes mellitus patients in relation to metabolic control and caries-associated risk factors. Caries Res 2002;36:31–5.10.1159/000057587Search in Google Scholar PubMed
16. de Pommereau V, Dargent-Paré C, Robert JJ, Brion M. Periodontal status in insulin-dependent diabetic adolescents. J Clin Periodontol 1992;19:628–32.10.1111/j.1600-051X.1992.tb01710.xSearch in Google Scholar PubMed
17. Sandholm L, Swanljung O, Rytömaa I, Kaprio EA, Mäenpää J. Morphotypes of the subgingival microflora in diabetic adolescents in Finland. J Periodontol 1989;60:526–8.10.1902/jop.1989.60.9.526Search in Google Scholar PubMed
18. Klokkevold PR, Maeley BL, Carranza FA. Influence of systemic disease and disorders on the periodontium. In: Newman MG, Takei HH, Carranza FA, editors. Carranza’s clinical periodontology, 9th ed. Philadelphia, PA: Saunders, 2002. p. 204–28.Search in Google Scholar
19. Hinrichs JE. The role of dental calculus and other predisposing factors. In: Newman MG, Takei HH, Carranza FA, editors. Carranza’s clinical periodontology, 9th ed. Philadelphia, PA: Saunders, 2002. p. 182–203.Search in Google Scholar
20. Vidya K, Shetty P, Anandakrishna L. Oral health and glycosylated hemoglobin among type 1 diabetes children in South India. J Indian Soc Pedod Prev Dent 2018;36:38–42.Search in Google Scholar PubMed
21. Rai K, Hegde AM, Kamath A, Shetty S. Dental caries and salivary alterations in type 1 diabetes. J Clin Pediatr Dent 2011;36:181–4.10.17796/jcpd.36.2.x436ln878221g364Search in Google Scholar PubMed
22. World Health Organisation. Oral Health Surveys: Basic Methods, 6th ed. Geneva, Switzerland: WHO, 2013.Search in Google Scholar
23. Loe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21;533–51.10.3109/00016356309011240Search in Google Scholar PubMed
24. Gheena S, Chandrasekhar T, Ramani P. Salivary characteristics of diabetic children. Braz J Oral Sci 2011;10:93–7.Search in Google Scholar
25. Miko S, Ambrus SJ, Sahafian S, Dinya E, Tamas G, et al. Dental caries and adolescents with type 1 diabetes. Br Dent J 2010;27;208:E12.10.1038/sj.bdj.2010.290Search in Google Scholar PubMed
26. Moore PA, Guggenheimer J, Etzel KR, Weyant RJ, Orchard T. Type 1 diabetes mellitus, xerostomia, and salivary flow rates. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;92:281–91.10.1067/moe.2001.117815Search in Google Scholar PubMed
27. Edblad E, Lundin SA, Sjödin B, Aman J. Caries and salivary status in young adults with type 1 diabetes. Swed Dent J 2001;25:53–60.Search in Google Scholar PubMed
28. Alavi AA, Amirhakimi E, Karami B. The prevalence of dental caries in 5–18-year-old insulin-dependent diabetics of Fars Province, southern Iran. Arch Iran Med 2006;9:254–60.Search in Google Scholar PubMed
29. Bolgül BS, Celenk S, Ayna BE, Atakul F, Uysal E. Evaluation of caries risk factors and effects of a fluoride-releasing adhesive material in children with insulin-dependent diabetes mellitus (IDDM): initial first-year results. Acta Odontol Scand 2004;62:289–92.10.1080/00016350410001766Search in Google Scholar PubMed
30. Siudikiene J, Machiulskiene V, Nyvad B, Tenovuo J, Nedzelskiene I. Dental caries and salivary status in children with type 1 diabetes mellitus, related to the metabolic control of the disease. Eur J Oral Sci 2006;114:8–14.10.1111/j.1600-0722.2006.00277.xSearch in Google Scholar PubMed
31. Samimi P, Zoratipour A, Fathpour K. A comparative study on dental caries prevalence in diabetic children in Isfahan in the summer of 2000. J Res Med Sci 2004;9:97–8.Search in Google Scholar
32. Akpata ES, Alomari Q, Mojiminiyi OA, Al-Sanae H. Caries experience among children with type 1 diabetes in Kuwait. Pediatr Dent 2012;34:468–72.Search in Google Scholar PubMed
33. López ME, Colloca ME, Páez RG, Schallmach JN, Koss MA, et al. Salivary characteristics of diabetic children. Braz Dent J 2003;14:26–31.10.1590/S0103-64402003000100005Search in Google Scholar PubMed
34. López del Valle LM, Ocasio-López C. Comparing the oral health status of diabetic and non-diabetic children from Puerto Rico: a case-control pilot study. P R Health Sci J 2011;30:123–7.Search in Google Scholar PubMed
35. Wegner H. Increment of caries in young diabetics. Caries Res 1975;9:90–1.10.1159/000260147Search in Google Scholar PubMed
36. Karjalainen KM, Knuuttila ML, Käär ML. Relationship between caries and level of metabolic balance in children and adolescents with insulin-dependent diabetes mellitus. Caries Res 1997;31:13–8.10.1159/000262367Search in Google Scholar PubMed
37. Twetman S, Nederfors T, Stahl B, Aronson S. Two-year longitudinal observations of salivary status and dental caries in children with insulin-dependent diabetes mellitus. Pediatr Dent 1992;14:184–8.Search in Google Scholar PubMed
38. Tagelsir A, Cauwels R, van Aken S, Vanobbergen J, Martens LC. Dental caries and dental care level (restorative index) in children with diabetes mellitus type 1. Int J Paediatr Dent 2011;21:13–22.10.1111/j.1365-263X.2010.01094.xSearch in Google Scholar PubMed
39. Lalla E, Cheng B, Lal S, Kaplan S, Softness B, et al. Diabetes mellitus promotes periodontal destruction in children. J Clin Periodontol 2007;34:294–8.10.1111/j.1600-051X.2007.01054.xSearch in Google Scholar PubMed
40. de Pommereau V, Dargent-Pare C, Robert JJ, Brion M. Periodontal status in insulin-dependent diabetic adolescents. J Clin Periodontol 1992;19:628–32.10.1111/j.1600-051X.1992.tb01710.xSearch in Google Scholar PubMed
41. Novaes AB Jr, Pereira AL, de Moraes N, Novaes AB. Manifestations of insulin-dependent diabetes mellitus in the periodontium of young Brazilian patients. J Periodontol 1991;62:116–22.10.1902/jop.1991.62.2.116Search in Google Scholar PubMed
42. Seppälä B, Seppälä M, Ainamo J. A longitudinal study on insulin-dependent diabetes mellitus and periodontal disease. J Clin Periodontol 1993;20:161–5.10.1111/j.1600-051X.1993.tb00338.xSearch in Google Scholar PubMed
43. Morain WD, Colen LB. Wound healing in diabetes mellitus. Clin Plast Surg 1990;17:493–501.10.1016/S0094-1298(20)30624-6Search in Google Scholar PubMed
44. Rosenberg CS. Wound healing in the patient with diabetes mellitus. Nurs Clin North Am 1990;25:247–61.10.1016/S0029-6465(22)00238-9Search in Google Scholar PubMed
45. McMillan DE, Utterback NG, La Puma J. Reduced erythrocyte deformability in diabetes. Diabetes 1978;27:895–901.10.2337/diab.27.9.895Search in Google Scholar PubMed
46. Kawamura K, Dohl T, Tamai K, Shirakawa M, Okamoto H, et al. Gingival tissue-produced inhibition of platelet aggregation and the loss of inhibition in streptozotocin-induced diabetic rats. J Periodontal Res 1988;23:87–90.10.1111/j.1600-0765.1988.tb01339.xSearch in Google Scholar PubMed
47. Andronikaki-Faldami A, Asimakopoulou G, Diamantikipioti A, Papadopoulou-Markopoulou K, Thalassinos N. Diabetes mellitus and periodontium. 1. Prevalence of periodontal disease in young insulin-dependent diabetics. Stomatologia (Athenai). 1990;47:73–86.Search in Google Scholar PubMed
48. Lal S, Cheng B, Kaplan S, Softness B, Greenberg E, et al. Gingival bleeding in 6- to 13-year-old children with diabetes mellitus. Pediatr Dent 2007;29:426–30.Search in Google Scholar PubMed
49. Orbak R, Simsek S, Orbak Z, Kavrut F, Colak M. The influence of type-1 diabetes mellitus on dentition and oral health in children and adolescents. Yonsei Med J 2008;49:357–65.10.3349/ymj.2008.49.3.357Search in Google Scholar PubMed PubMed Central
50. Gislen G, Nilsson KO, Matsson L. Gingival inflammation in diabetic children related to degree of metabolic control. Acta Odontol Scand 1980;38:241–6.10.3109/00016358009003496Search in Google Scholar PubMed
©2018 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Original Articles
- Targeted next generation sequencing in patients with maturity-onset diabetes of the young (MODY)
- Assessment of dental caries and gingival status among a group of type 1 diabetes mellitus and healthy children of South India – a comparative study
- Early adiposity rebound in patients with Prader-Willi syndrome
- Arterial stiffness as a measure of cardiovascular risk in obese adolescents and adolescents with diabetes type 1
- Dysregulated glucose homeostasis in congenital central hypoventilation syndrome
- Do parents of children with metabolic diseases benefit from the Triple P – Positive Parenting Program? A pilot study
- Early higher dosage of alglucosidase alpha in classic Pompe disease
- Insulin resistance in children with familial hyperlipidemia
- Insulin resistance linked to subtle myocardial dysfunction in normotensive Turner syndrome young patients without structural heart diseases
- Acetylcholinesterase activity and bone biochemical markers in premature and full-term neonates
- Baseline characteristics of gender dysphoric youth
- Case Reports
- Multi-disciplinary evaluation of a 5-month-old with hypertrophic cardiomyopathy related to a functional adrenocortical tumor
- A case of an infant with extremely low birth weight and hypothyroidism associated with massive cutaneous infantile hemangioma
- Possible hints and pitfalls in diagnosing Peutz-Jeghers syndrome
Articles in the same Issue
- Frontmatter
- Original Articles
- Targeted next generation sequencing in patients with maturity-onset diabetes of the young (MODY)
- Assessment of dental caries and gingival status among a group of type 1 diabetes mellitus and healthy children of South India – a comparative study
- Early adiposity rebound in patients with Prader-Willi syndrome
- Arterial stiffness as a measure of cardiovascular risk in obese adolescents and adolescents with diabetes type 1
- Dysregulated glucose homeostasis in congenital central hypoventilation syndrome
- Do parents of children with metabolic diseases benefit from the Triple P – Positive Parenting Program? A pilot study
- Early higher dosage of alglucosidase alpha in classic Pompe disease
- Insulin resistance in children with familial hyperlipidemia
- Insulin resistance linked to subtle myocardial dysfunction in normotensive Turner syndrome young patients without structural heart diseases
- Acetylcholinesterase activity and bone biochemical markers in premature and full-term neonates
- Baseline characteristics of gender dysphoric youth
- Case Reports
- Multi-disciplinary evaluation of a 5-month-old with hypertrophic cardiomyopathy related to a functional adrenocortical tumor
- A case of an infant with extremely low birth weight and hypothyroidism associated with massive cutaneous infantile hemangioma
- Possible hints and pitfalls in diagnosing Peutz-Jeghers syndrome