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Effect of graded doses of Caesalpinia bonducella seed extract on ovary and uterus in albino rats

  • Kanchan R. Salunke , R. Nazeer Ahmed EMAIL logo , Shambanagouda R. Marigoudar and Lilaram
Published/Copyright: June 17, 2011
Journal of Basic and Clinical Physiology and Pharmacology
From the journal Volume 22 Issue 1-2

Abstract

Histological changes observed under light microscope illustrate follicular degeneration in ovary, vacuolation and mild disorganization of uterus on treatment with graded doses of alcohol seed extract of Caesalpinia bonducella. There was a significant decrease (p≤0.05) in duration of estrous cycle and mean ovarian weight. However, there were no uniform variations in mean uterine weight, serum estradiol and progesterone level. The results suggest that alcohol seed extract of C. bonducella has antiestrogenic property, possibly acting via inhibition of estrogen secretion.


Corresponding author: Dr. R. Nazeer Ahmed, Professor, Postgraduate Department of Studies and Research in Zoology, Karnatak University, Dharwad 580 003, Karnataka, India

Published Online: 2011-06-17
Published in Print: 2011-06-01

©2011 by Walter de Gruyter Berlin Boston

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