Effectiveness of electrical vestibular nerve stimulation on the range of motion in patients with Parkinson’s disease

Sai Sailesh Kumar Goothy; Sudhir Gawarikar; Anita Choudhary; Potey Gajanan Govind; Manju Purohit; Ashish Pathak; Rohit Singh Chouhan; Zaki Ali; Mini Tiwari; Mahadik Vijay Khanderao

doi:10.1515/jbcpp-2022-0138

Article

Effectiveness of electrical vestibular nerve stimulation on the range of motion in patients with Parkinson’s disease

Sai Sailesh Kumar Goothy , Sudhir Gawarikar , Anita Choudhary , Potey Gajanan Govind , Manju Purohit , Ashish Pathak , Rohit Singh Chouhan , Zaki Ali , Mini Tiwari and Mahadik Vijay Khanderao

Published/Copyright: October 10, 2022

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From the journal Journal of Basic and Clinical Physiology and Pharmacology Volume 34 Issue 6

Abstract

Objectives

The present study was undertaken to observe the effectiveness of electrical vestibular stimulation on the range of motion (ROM) in patients with Parkinson’s disease (PD).

Methods

The present study was a randomized controlled trial (ClinicalTrials.gov Identifier: NCT04450550). The study participants were assessed at three points of time. After recording baseline cognitive functions, electrical vestibular nerve stimulation was administered to the intervention group and placebo stimulation was administered to the control group for 12 weeks. Post-intervention parameters were recorded after 6 weeks and after 12 weeks after the intervention in both control and intervention groups. A total of 30 cases of PD, including both males and females were recruited in the study by convenient sampling after obtaining written informed consent. All ROM and flexibility measurements were recorded using a universal goniometer and standard protocol with help of an experienced physiotherapist at our hospital.

Results

There was a significant improvement in the hip internal and external rotation right and left sides. There was a significant improvement in the hip extension right and left. There was a significant improvement in the ankle plantarflexion left and ankle dorsiflexion right and left followed by the intervention. There was a significant decline in the hip internal rotation on right and left sides. There was a significant decline in the hip extension and ankle dorsiflexion on the left side.

Conclusions

The study results confirm the improvement of motor activities of patients with PD followed by vestibular stimulation. Further detailed studies are recommended to support the application of vestibular stimulation as an alternative therapy in the management of motor functions in patients with PD.

Keywords: motor activities; Parkinson’s disease; vestibular stimulation

Corresponding author: Sai Sailesh Kumar Goothy, Department of Physiology, R.D. Gardi Medical College, Ujjain, M.P., India, Phone: +919061076459, E-mail: dr.saisailesh@gmail.com

Funding source: Indian Council of Medical Research

Award Identifier / Grant number: Indian Council of Medical Research (2020 1352) (sa

Acknowledgments

Our sincere thanks to Dr. Jason McKeown, CEO of Neurovalens for providing the electrical vestibular nerve stimulators to our study. We also thank all the participants of the study for their support throughout the study. Special thanks to our Dean, R.D. Gardi Medical College for providing all required resources to accomplish the study.

Research funding: The study was funded by the Indian Council of Medical Research (2020 1352) (sanction letter 5/3/8/50/2020- ITR).
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interests: The authors state no conflict of interest.
Informed consent: Informed consent was obtained from all individuals included in this study.
Ethical approval: The local Institutional Review Board deemed the study exempt from review.

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Received: 2022-05-16

Accepted: 2022-09-25

Published Online: 2022-10-10

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Articles in the same Issue

https://doi.org/10.1515/jbcpp-2022-0138

Keywords for this article

motor activities; Parkinson’s disease; vestibular stimulation