Numerical study on the effect of planar normal and Halbach magnet arrays on micromixing
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Dariush Bahrami
Abstract
The effective mixing process is critical in biological and chemical processes. The main objective of the present study is to investigate the influence of normal and Halbach magnet arrays on the mixing performance of a three-inlet micromixer numerically. In this microdevice, ferrofluid is injected into the center inlet, and water is injected into two other inlets. The influence of Remanent Flux Density Norm (RFDN), number of magnets, magnet distance from the main microchannel entrance, and inlet flow rate is considered. It is revealed that the micromixer with magnets exhibits a 165% improvement in the mixing efficiency compared to the one with no magnetic field. The results show that increasing the magnetic field does not always increase the mixing quality. Even in some cases, it has a negative effect. It is demonstrated that the mixing efficiency is strongly influenced by the magnet arrangement. An optimal position is found for the magnet arrangement to achieve the maximum mixing efficiency of 91%. Contrary to the normal configuration, Halbach magnet array creates a parabolic profile for flux density. Halbach array can improve the mixing performance, depending on all magnets’ RFDN. The proposed microchannel can be used as a useful device for biological applications.
Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
References
Azimi, N., and M. Rahimi. 2017. “Magnetic Nanoparticles Stimulation to Enhance Liquid-Liquid Two-Phase Mass Transfer under Static and Rotating Magnetic Fields.” Journal of Magnetism and Magnetic Materials 422: 188–96, https://doi.org/10.1016/j.jmmm.2016.08.092.Search in Google Scholar
Bayareh, M., M. N. Ashani, and A. Usefian. 2019. “Active and Passive Micromixers: A Comprehensive Review.” Chemical Engineering and Processing-Process Intensification 147, 107771. https://doi.org/10.1016/j.cep.2019.107771.Search in Google Scholar
Cai, G., L. Xue, H. Zhang, and J. Lin. 2017. “A Review on Micromixers.” Micromachines 8: 274, https://doi.org/10.3390/mi8090274.Search in Google Scholar PubMed PubMed Central
Fateen, S.-E. K., and M. Magdy. 2015. “Three Dimensional Simulation of Negative-Magnetophoretic Filtration of Non-Magnetic Nanoparticles.” Chemical Engineering Research and Design 95: 69–78, https://doi.org/10.1016/j.cherd.2015.01.007.Search in Google Scholar
Hejazian, M., D.-T. Phan, and N.-T. Nguyen. 2016. “Mass Transport Improvement in Microscale Using Diluted Ferrofluid and a Non-Uniform Magnetic Field.” RSC advances 6: 62439–44, https://doi.org/10.1039/c6ra11703a.Search in Google Scholar
Kitenbergs, G., A. Tatuļčenkovs, L. Puķina, and A. Cēbers. 2018. “Gravity Effects on Mixing with Magnetic Micro-Convection in Microfluidics.” The European Physical Journal E 41: 138, https://doi.org/10.1140/epje/i2018-11749-9.Search in Google Scholar PubMed
Kumar, C., M. Hejazian, C. From, S. C. Saha, E. Sauret, Y. Gu, and N. T. Nguyen. 2019. “Modeling of Mass Transfer Enhancement in a Magnetofluidic Micromixer.” Physics of Fluids 31, 063603, https://doi.org/10.1063/1.5093498.Search in Google Scholar
Liu, W., L. Nie, F. Li, Z. P. Aguilar, H. Xu, Y. Xiong, F. Fu, and H. Xu. 2016. “Folic Acid Conjugated Magnetic Iron Oxide Nanoparticles for Nondestructive Separation and Detection of Ovarian Cancer Cells from Whole Blood.” Biomaterials science 4: 159–66, https://doi.org/10.1039/c5bm00207a.Search in Google Scholar PubMed
Liu, M., X. Han, Q. Cao, and L. Li. 2017. “Performance Analysis of a Microfluidic Mixer Based on High Gradient Magnetic Separation Principles.” Journal of Physics D: Applied Physics 50: 365004, https://doi.org/10.1088/1361-6463/aa7eb7.Search in Google Scholar
Maleki, M. A., M. Soltani, N. Kashaninejad, and N.-T. Nguyen. 2019. “Effects of Magnetic Nanoparticles on Mixing in Droplet-Based Microfluidics.” Physics of Fluids 31, 032001, https://doi.org/10.1063/1.5086867.Search in Google Scholar
Mody, V. V., A. Cox, S. Shah, A. Singh, W. Bevins, and H. Parihar. 2014. “Magnetic Nanoparticle Drug Delivery Systems for Targeting Tumor.” Applied Nanoscience 4: 385–92, https://doi.org/10.1007/s13204-013-0216-y.Search in Google Scholar
Mohammadi, F., M. Rahimi, A. Parvareh, and M. Feyzi. 2017. “Stimulation of Magnetic Nanoparticles to Intensify Transesterification of Soybean Oil in Micromixers for Biodiesel Production.” Chemical Engineering and Processing: Process Intensification 122: 109–21, https://doi.org/10.1016/j.cep.2017.10.007.Search in Google Scholar
Munaz, A., M. J. Shiddiky, and N.-T. Nguyen. 2018a. “Recent Advances and Current Challenges in Magnetophoresis Based Micro Magnetofluidics.” Biomicrofluidics 12, 031501, https://doi.org/10.1063/1.5035388.Search in Google Scholar PubMed PubMed Central
Munaz, A., M. J. Shiddiky, and N.-T. Nguyen. 2018b. “Magnetophoretic Separation of Diamagnetic Particles through Parallel Ferrofluid Streams.” Sensors and Actuators B: Chemical 275: 459–69, https://doi.org/10.1016/j.snb.2018.07.176.Search in Google Scholar
Nam, J., W. S. Jang, and C. S. Lim. 2018. “Micromixing Using a Conductive Liquid-Based Focused Surface Acoustic Wave (CL-FSAW).” Sensors and Actuators B: Chemical 258: 991–7, https://doi.org/10.1016/j.snb.2017.11.188.Search in Google Scholar
Nazari, M., P.-Y. A. Chuang, J. A. Esfahani, and S. Rashidi. 2020. “A Comprehensive Geometrical Study on an Induced-Charge Electrokinetic Micromixer Equipped with Electrically Conductive Plates.” International Journal of Heat and Mass Transfer 146: 118892, https://doi.org/10.1016/j.ijheatmasstransfer.2019.118892.Search in Google Scholar
Nouri, D., A. Zabihi-Hesari, and M. Passandideh-Fard. 2017. “Rapid Mixing in Micromixers Using Magnetic Field.” Sensors and Actuators A: Physical 255: 79–86, https://doi.org/10.1016/j.sna.2017.01.005.Search in Google Scholar
Oh, D.-W., J. S. Jin, J. H. Choi, H.-Y. Kim, and J. S. Lee. 2007. “A Microfluidic Chaotic Mixer Using Ferrofluid.” Journal of Micromechanics and Microengineering 17: 2077, https://doi.org/10.1088/0960-1317/17/10/020.Search in Google Scholar
Saadat, M., M. B. Shafii, and M. Ghassemi. 2020a. “Numerical Investigation on Mixing Intensification of Ferrofluid and Deionized Water inside a Microchannel Using Magnetic Actuation Generated by Embedded Microcoils for Lab-On-Chip Systems.” Chemical Engineering and Processing-Process Intensification 147: 107727, https://doi.org/10.1016/j.cep.2019.107727.Search in Google Scholar
Saadat, M., M. Ghassemi, and M. B. Shafii. 2020b. “Numerical Investigation on the Effect of External Varying Magnetic Field on the Mixing of Ferrofluid with Deionized Water inside a Microchannel for Lab-on-Chip Systems.” Energy Sources, Part A: Recovery, Utilization, and Environmental Effects: 1–13, https://doi.org/10.1080/15567036.2020.1728440.Search in Google Scholar
Seo, H.-S., J.-C. Lee, I.-J. Hwang, and Y.-J. Kim. 2014. “Flow Characteristics of Ferrofluid in a Microchannel with Patterned Blocks.” Materials Research Bulletin 58: 10–14, https://doi.org/10.1016/j.materresbull.2014.03.027.Search in Google Scholar
Tsai, T.-H., D.-S. Liou, L.-S. Kuo, and P.-H. Chen. 2009. “Rapid Mixing between Ferro-Nanofluid and Water in a Semi-active Y-type Micromixer.” Sensors and Actuators A: Physical 153: 267–73, https://doi.org/10.1016/j.sna.2009.05.004.Search in Google Scholar
Usefian, A., and M. Bayareh. 2019. “Numerical and Experimental Study on Mixing Performance of a Novel Electro-Osmotic Micro-mixer.” Meccanica 54: 1149–62, https://doi.org/10.1007/s11012-019-01018-y.Search in Google Scholar
Usefian, A., and M. Bayareh. 2020. “Numerical and Experimental Investigation of an Efficient Convergent-Divergent Micromixer.” Meccanica 55: 1025–35, https://doi.org/10.1007/s11012-020-01142-0.Search in Google Scholar
Usefian, A., M. Bayareh, and A. A. Nadooshan. 2019. “Rapid Mixing of Newtonian and Non-Newtonian Fluids in a Three-Dimensional Micro-mixer Using Non-uniform Magnetic Field.” Journal of Heat and Mass Transfer Research 6 (1): 55–61. https://doi.org/10.22075/jhmtr.2018.15611.1218.Search in Google Scholar
Wang, Z., V. Varma, H. M. Xia, Z. Wang, and R. V. Ramanujan. 2015. “Spreading of a Ferrofluid Core in Three-Stream Micromixer Channels.” Physics of Fluids 27, 052004, https://doi.org/10.1063/1.4919927.Search in Google Scholar
Wen, C. Y., K. P. Liang, H. Chen, and L. M. Fu. 2011. “Numerical Analysis of a Rapid Magnetic Microfluidic Mixer.” Electrophoresis 32: 3268–76, https://doi.org/10.1002/elps.201100254.Search in Google Scholar PubMed
Zhou, R., A. N. Surendran, M. Mejulu, and Y. Lin. 2020. “Rapid Microfluidic Mixer Based on Ferrofluid and Integrated Microscale NdFeB-PDMS Magnet.” Micromachines 11: 29. https://doi.org/10.3390/mi11010029.Search in Google Scholar PubMed PubMed Central
Zhu, G.-P., and N.-T. Nguyen. 2012a. “Rapid Magnetofluidic Mixing in a Uniform Magnetic Field.” Lab on a Chip 12: 4772–80, https://doi.org/10.1039/c2lc40818j.Search in Google Scholar PubMed
Zhu, G.-P., and N.-T. Nguyen. 2012b. “Magnetofluidic Spreading in Microchannels.” Microfluidics and Nanofluidics 13: 655–63, https://doi.org/10.1007/s10404-012-1056-x.Search in Google Scholar
Zolgharni, M., S. Azimi, M. Bahmanyar, and W. Balachandran. 2007. “A Numerical Design Study of Chaotic Mixing of Magnetic Particles in a Microfluidic Bio-Separator.” Microfluidics and Nanofluidics 3: 677–87, https://doi.org/10.1007/s10404-007-0160-9.Search in Google Scholar
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Articles in the same Issue
- Review
- Separation and purification of fatty acids by membrane technology: a critical review
- Articles
- Investigation of the flow patterns and power requirements in agitated systems: effects of the design of baffles and vessel base
- Computational fluid dynamics simulation of solid-liquid suspension characteristics in a stirred tank with punched circle package impellers
- Fischer-Tropsch reaction mixture permeation through a silicalite-1 membrane reactor and its effect on the produced hydrocarbons distribution
- Influence of the amine alkyl-chain upon carbon dioxide absorption in G-L-L reactor
- Catalytic performance of cerium-modified ZSM-5 zeolite as a catalyst for the esterification of glycerol with acetic acid
- Numerical study on the effect of planar normal and Halbach magnet arrays on micromixing
- The optimization and statistical analysis of fermentative hydrogen production using Taguchi method
- Mechanism of recovery processes for rare earth and iron from Bayan Obo tailings
- Short Communication
- Design optimization of micromixer with circular mixing chambers (M-CMC) using Taguchi-based grey relational analysis
