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Teenage menstrual dysfunction: an overview

  • Mehrukh Zehravi , Mudasir Maqbool ORCID logo EMAIL logo and Irfat Ara
Published/Copyright: September 19, 2022

Abstract

When a girl experiences her first period, she starts a new phase of her life and becomes biologically capable of becoming a mother and giving birth to a child. Girls’ hypothalamus-pituitary-ovary axis reaches “axial maturity” during puberty, when they are between the ages of 8 and 13 years old. Secondary biological features, including as growth, body-shape changes in females, breast growth, hair growth on the vulva, and hair growth on the axillary pits, are often observed during this era. The first menstruation, or menarche, is also commonly observed during this time. During the menstrual cycle, a woman’s ability to conceive and give birth is at the core of her reproductive life.


Corresponding author: Mudasir Maqbool, Research Scholar, Department of Pharmaceutical Sciences, University Of Kashmir, Srinagar, Jammu and Kashmir, 190006, India, E-mail:

Acknowledgement

Authors would like to thank all the authors whose work has been reviewed while preparing this manuscript.

  1. Research funding: None.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Conflict of interest: None.

References

1. Huffman, JW. Delayed female sexual maturation: how to approach differential diagnosis. Postgrad Med 1985;78:239–60. https://doi.org/10.1080/00325481.1985.11699099.Search in Google Scholar PubMed

2. Orben, A, Tomova, L, Blakemore, S-J. The effects of social deprivation on adolescent development and mental health. Lancet Child Adolesc Health 2020;4:634–40. https://doi.org/10.1016/s2352-4642(20)30186-3.Search in Google Scholar

3. Rapee, RM, Oar, EL, Johnco, CJ, Forbes, MK, Fardouly, J, Magson, NR, et al.. Adolescent development and risk for the onset of social-emotional disorders: a review and conceptual model. Behav Res Ther 2019;123:103501. https://doi.org/10.1016/j.brat.2019.103501.Search in Google Scholar PubMed

4. Resnick, MD, Catalano, RF, Sawyer, SM, Viner, R, Patton, GC. Seizing the opportunities of adolescent health. Lancet 2012;379:1564–7. https://doi.org/10.1016/s0140-6736(12)60472-3.Search in Google Scholar PubMed

5. Trickett, PK, Negriff, S, Ji, J, Peckins, M. Child maltreatment and adolescent development. J Res Adolesc 2011;21:3–20. https://doi.org/10.1111/j.1532-7795.2010.00711.x.Search in Google Scholar

6. Patton, GC, Sawyer, SM, Santelli, JS, Ross, DA, Afifi, R, Allen, NB, et al.. Our future: a Lancet commission on adolescent health and wellbeing. Lancet 2016;387:2423–78. https://doi.org/10.1016/s0140-6736(16)00579-1.Search in Google Scholar PubMed PubMed Central

7. Malin, HM, Saleh, FM. Sexual development and behavior in children and adolescents. In: Adolescent sexual behavior in the digital age: Considerations for clinicians, legal professionals, and educators; 2014:43–61 pp.10.1093/med/9780199945597.003.0003Search in Google Scholar

8. Zarrett, N, Eccles, J. The passage to adulthood: challenges of late adolescence. New Dir Youth Dev 2006;2006:13–28. https://doi.org/10.1002/yd.179.Search in Google Scholar PubMed

9. Zehravi, M, Maqbool, M, Ara, I. Polycystic ovary syndrome and reproductive health of women: a curious association. Int J Adolesc Med Health 2021;33:333–7. https://doi.org/10.1515/ijamh-2021-0031.Search in Google Scholar PubMed

10. Maqbool, M, Khan, M, Mohammad, M, Adesina, MA, Fekadu, G. Awareness about reproductive health in adolescents and youth: a review. J Appl Pharm Sci Res 2019;2:1–5. https://doi.org/10.31069/japsr.v2i3.1.Search in Google Scholar

11. Wiele, RLV, Bogumil, J, Dyrenfurth, I, Ferin, M, Jewelewicz, R, Warren, M, et al.. Mechanisms regulating the menstrual cycle in women. In: Proceedings of the 1969 Laurentian Hormone Conference: Elsevier; 1970:63–103 pp.10.1016/B978-0-12-571126-5.50006-6Search in Google Scholar PubMed

12. Liu, Y, Gold, EB, Lasley, BL, Johnson, WO. Factors affecting menstrual cycle characteristics. Am J Epidemiol 2004;160:131–40. https://doi.org/10.1093/aje/kwh188.Search in Google Scholar PubMed

13. Mihm, M, Gangooly, S, Muttukrishna, S. The normal menstrual cycle in women. Anim Reprod Sci 2011;124:229–36. https://doi.org/10.1016/j.anireprosci.2010.08.030.Search in Google Scholar PubMed

14. Hawkins, SM, Matzuk, MM. The menstrual cycle: basic biology. Ann N Y Acad Sci 2008;1135:10–8. https://doi.org/10.1196/annals.1429.018.Search in Google Scholar PubMed PubMed Central

15. Carmichael, MA, Thomson, RL, Moran, LJ, Wycherley, TP. The impact of menstrual cycle phase on athletes’ performance: a narrative review. Int J Environ Res Publ Health 2021;18:1667. https://doi.org/10.3390/ijerph18041667.Search in Google Scholar PubMed PubMed Central

16. Schmalenberger, KM, Tauseef, HA, Barone, JC, Owens, SA, Lieberman, L, Jarczok, MN, et al.. How to study the menstrual cycle: practical tools and recommendations. Psychoneuroendocrinology 2021;123:104895. https://doi.org/10.1016/j.psyneuen.2020.104895.Search in Google Scholar PubMed PubMed Central

17. Perlman, B, Kulak, D, Goldsmith, LT, Weiss, G. The etiology of menopause: not just ovarian dysfunction but also a role for the central nervous system. Glob Reprod Health 2018;3:e8. https://doi.org/10.1097/grh.0000000000000008.Search in Google Scholar

18. George, SA, Williamson Lewis, R, Schirmer, DA, Effinger, KE, Spencer, JB, Mertens, AC, et al.. Early detection of ovarian dysfunction by anti-Mullerian hormone in adolescent and young adult-aged survivors of childhood cancer. J Adolesc Young Adult Oncol 2019;8:18–25. https://doi.org/10.1089/jayao.2018.0080.Search in Google Scholar PubMed

19. Zhou, S, Xi, Y, Chen, Y, Zhang, Z, Wu, C, Yan, W, et al.. Ovarian dysfunction induced by chronic whole‐body PM2. 5 exposure. Small 2020;16:2000845. https://doi.org/10.1002/smll.202000845.Search in Google Scholar PubMed

20. Wang, M, Zhao, D, Xu, L, Guo, W, Nie, L, Lei, Y, et al.. Role of PCSK9 in lipid metabolic disorders and ovarian dysfunction in polycystic ovary syndrome. Metabolism 2019;94:47–58. https://doi.org/10.1016/j.metabol.2019.02.002.Search in Google Scholar PubMed

21. Neinstein, LS, Gordon, CM, Katzman, DK, Rosen, DS. Handbook of adolescent health care: Lippincott Williams & Wilkins; 2008.Search in Google Scholar

22. Wang, Y-X, Arvizu, M, Rich-Edwards, JW, Stuart, JJ, Manson, JE, Missmer, SA, et al.. Menstrual cycle regularity and length across the reproductive lifespan and risk of premature mortality: prospective cohort study. BMJ 2020;371. https://doi.org/10.1136/bmj.m3464.Search in Google Scholar PubMed PubMed Central

23. Huppert, LC. Ovarian dysfunction in the adolescent. In: Adolescent gynecology: Springer; 1983:27–53 pp.10.1007/978-1-4615-8324-0_3Search in Google Scholar

24. Kelsey, MM, Braffett, BH, Geffner, ME, Levitsky, LL, Caprio, S, McKay, SV, et al.. Menstrual dysfunction in girls from the treatment options for type 2 diabetes in adolescents and youth (TODAY) study. J Clin Endocrinol Metabol 2018;103:2309–18. https://doi.org/10.1210/jc.2018-00132.Search in Google Scholar PubMed PubMed Central

25. Van den Akker, OB. Reproductive health psychology: John Wiley & Sons; 2012.10.1002/9781119968382Search in Google Scholar

26. Baker, ER. Menstrual dysfunction and hormonal status in athletic women: a review. Fertil Steril 1981;36:691–6. https://doi.org/10.1016/s0015-0282(16)45908-x.Search in Google Scholar PubMed

27. Harlow, SD, Campbell, OM. Menstrual dysfunction: a missed opportunity for improving reproductive health in developing countries. Reprod Health Matters 2000;8:142–7. https://doi.org/10.1016/s0968-8080(00)90016-8.Search in Google Scholar PubMed

28. Zelnik, M, Kim, YJ. Sex education and its association with teenage sexual activity, pregnancy and contraceptive use. Fam Plann Perspect 1982;14:117–26. https://doi.org/10.2307/2134709.Search in Google Scholar

29. Fields, J. Risky lessons: sex education and social inequality: Rutgers University Press; 2008.Search in Google Scholar

30. Buston, K, Wight, D. The salience and utility of school sex education to young women. Sex Educ 2002;2:233–50. https://doi.org/10.1080/1468181022000025794.Search in Google Scholar

31. Ekstrand, M, Engblom, C, Larsson, M, Tydén, T. Sex education in Swedish schools as described by young women. Eur J Contracept Reprod Health Care 2011;16:210–24. https://doi.org/10.3109/13625187.2011.561937.Search in Google Scholar PubMed

32. Buller, AM, Schulte, MC. Aligning human rights and social norms for adolescent sexual and reproductive health and rights. Reprod Health Matters 2018;26:38–45. https://doi.org/10.1080/09688080.2018.1542914.Search in Google Scholar

Received: 2022-02-26
Accepted: 2022-07-12
Published Online: 2022-09-19

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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