Home Medicine Impact of an autonomous delivery robot on sample turnaround time in a clinical laboratory: an early evaluation of first implementation
Article
Licensed
Unlicensed Requires Authentication

Impact of an autonomous delivery robot on sample turnaround time in a clinical laboratory: an early evaluation of first implementation

  • ORCID logo EMAIL logo , , , , , , and
Published/Copyright: December 10, 2025

Abstract

Objectives

The aim of this study was to evaluate the impact of introducing an autonomous courier in a clinical laboratory, focusing on specimen turnaround time (TAT). We assessed whether high-frequency robotic transport from the central accessioning area to analytical sections could reduce delays and variability compared with manual delivery.

Methods

We retrospectively analyzed routine lithium–heparin glucose specimens processed during the initial days of robot deployment (13–23 May 2025, weekdays, 08:00–16:00) and compared them with the same period in 2024 under manual transport. TAT was defined as the interval from check-in at accessioning to technical validation in the Laboratory Information System (LIS). Data were assessed globally and stratified by time of day, examining changes in central tendency, dispersion, and extreme delays.

Results

In total, 6,299 samples in 2024 and 5,759 in 2025 were analyzed, showing a leftward shift of the distribution with fewer delay. In 2025, the mean TAT decreased from 122.64 to 106.72 min, the median from 112 to 101 min, and dispersion tightened. Stratification by time of day also demonstrated consistent improvements.

Conclusions

Even in its earliest days of operation, the delivery robot reduced TAT and variability, converting specimen transport from batch runs into near-continuous flow. These findings highlight ease of adoption and the potential of robotic transport to improve speed, predictability, and safety in intralaboratory logistics. Further validation across longer periods and additional laboratory sections is warranted.


Corresponding author: Jacopo Gervasoni, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, E-mail:
Giovanni Arcuri and Andrea Urbani share senior authorship.
  1. Research ethics: Not applicable.

  2. Informed consent: Not applicable.

  3. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  4. Use of Large Language Models, AI and Machine Learning Tools: None declared.

  5. Conflict of interest: The authors state no conflict of interest.

  6. Research funding: None declared.

  7. Data availability: Not applicable.

References

1. Hawker, CD. Laboratory automation: total and subtotal automation. Clin Lab Med 2007;27:749–70. https://doi.org/10.1016/j.cll.2007.07.010-PMID:17950896.10.1016/j.cll.2007.07.010Search in Google Scholar PubMed

2. Armbruster, DA, Overcash, DR, Reyes, J. Clinical chemistry laboratory automation in the 21st century – amat Victoria Curam. Clin Biochem Rev 2014;35:143–53.Search in Google Scholar

3. Rossetti, MD, Trzcinski, GF, Syverud, SA. Simulation of robotic courier deliveries in hospital distribution services. Health Care Manag Sci 2000;3:201–13. https://doi.org/10.1023/a:1019049609350-PMID:10907323.10.1023/A:1019049609350Search in Google Scholar

4. Holman, JW, Mifflin, TE, Felder, RA, Demers, LM. Evaluation of an automated preanalytical robotic workstation at two academic health centers. Clin Chem 2002;48:540–8. https://doi.org/10.1093/clinchem/48.3.540.Search in Google Scholar

5. Felder, RA. Push for patient safety is nudge for automation. CAP Today 2003;17:24–7.Search in Google Scholar

6. Felder, RA. Medical automation: a technologically enhanced work environment to reduce the burden of care on nursing staff and a solution to the health care cost crisis. Nurs Outlook 2003;51:67–71. https://doi.org/10.1016/s0029-6554(03)00102-7-PMID:12830121.10.1016/S0029-6554(03)00102-7Search in Google Scholar

7. Lippi, G, Chance, JJ, Church, S, Dazzi, P, Fontana, R, Giavarina, D, et al.. Preanalytical quality improvement: from dream to reality. Clin Chem Lab Med 2011;49:1113–26. https://doi.org/10.1515/CCLM.2011.600-PMID:21517699.10.1515/CCLM.2011.600Search in Google Scholar PubMed

8. Alwan, M, Leachtenauer, J, Dalal, S, Kell, S, Turner, B, Mack, D, et al.. Validation of rule-based inference of selected independent activities of daily living. Telemed J E Health 2005;11:594–9. https://doi.org/10.1089/tmj.2005.11.594-PMID:16250824.10.1089/tmj.2005.11.594Search in Google Scholar PubMed

9. Alwan, M, Dalal, S, Mack, D, Kell, S, Turner, B, Leachtenauer, J, et al.. Impact of monitoring technology in assisted living: outcome pilot. IEEE Trans Inf Technol Biomed 2006;10:192–8. https://doi.org/10.1109/titb.2005.855552-PMID:16445264.10.1109/TITB.2005.855552Search in Google Scholar PubMed

10. First Alert 4 News. How a robot is making a big difference for a local hospital. KMOV4 2024. Available from: https://www.firstalert4.com/video/2024/06/14/how-robot-is-making-big-difference-local-hospital.Search in Google Scholar

11. Robotics, P. FlashBot product brochure. Shenzhen (CN): Pudu Robotics; 2022. Available from: https://static.generation-robots.com/media/brochure-flashbot-v2-en.pdf.Search in Google Scholar

12. European Parliament and Council of the European Union. Directive 2014/33/EU of the European parliament and of the council of 26 February 2014 on the harmonisation of the laws of the member states relating to lifts and safety components for lifts. Off J Eur Union 2014;L96:251–90.Search in Google Scholar

13. American Society of Mechanical Engineers (ASME). ASME A17.1/CSA B44-2022: safety code f calators. New York: ASME; 2022. Available from: https://blog.ansi.org/ansi/asme-a17-1-2022-safety-code-elevator-csa-b44/.Search in Google Scholar

14. Standardization Administration of China (SAC). GB/T 7588.1-2020: safety rules for the construction and installation of lifts – part 1: passenger and goods passenger lifts. Beijing: AC; 2020. Available from: https://www.chinesestandard.net/PDF/English.aspx/GBT7588.1-2020.Search in Google Scholar

Received: 2025-10-10
Accepted: 2025-11-27
Published Online: 2025-12-10
Published in Print: 2026-03-26

© 2025 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Reshaping laboratory medicine through technological advances
  4. Reviews
  5. Capillary blood in core laboratories: current and future challenges
  6. Artificial intelligence and machine learning in thrombosis and hemostasis: a scoping review of clinical and laboratory applications, challenges, and future directions
  7. Opinion Papers
  8. Hierarchy of reference interval models: advancing laboratory data interpretation
  9. Reimagining External Quality Assessment for precision medicine: a perspective from biochemistry laboratories
  10. Science, Quality and Value of Laboratory Medicine
  11. Guidelines and Recommendations
  12. Recommendations from the IFCC Working Group on Laboratory Errors and Patient Safety for the Global Adoption of an Essential Quality Indicators Panel in Laboratory Medicine
  13. Addressing the silent epidemic of recreational nitrous oxide use: a position, call to action and recommendations by the European Federation of Clinical Chemistry and Laboratory Medicine Committee on Biological Markers of Nitrous Oxide Abuse
  14. General Clinical Chemistry and Laboratory Medicine
  15. Assessment of drone transport for biological samples: a real-world experience at a tertiary hospital
  16. Impact of an autonomous delivery robot on sample turnaround time in a clinical laboratory: an early evaluation of first implementation
  17. Implementation of an automated alert system of critical results in hospitalized and emergency patients
  18. Comparison of blood sample quality and test results between robotic and manual venipuncture: a pilot study
  19. At-home blood collection for clinical chemistry analyses in a kidney transplant population: a feasibility study
  20. Clinical validation of a DBS-based LC-MS/MS method for 25-hydroxyvitamin D: from lab sampling to home sampling
  21. Comparative analysis of three platforms for serum NfL quantification in healthy controls and MS patients
  22. Uracil in plasma: comparison of two in-house-developed LC-MS/MS methods
  23. Assessment for potential bias in multiplexed IL-10 and TNF-α from plex count
  24. Hematology and Coagulation
  25. A specific-neonatal hemolysis correction model for accurate potassium assessment in blood samples with in vitro hemolysis
  26. Cancer Diagnostics
  27. Analytical verification and comparative assessment of the new Atellica IM high-sensitivity prostate specific antigen assay
  28. Extended verification of an automated MALDI-TOF mass spectrometry system for high throughput serum M-protein measurement
  29. Cardiovascular Diseases
  30. Performance evaluation of a new high-sensitivity cardiac troponin T assay: hs-cTnT (CLIA) assay
  31. Infectious Diseases
  32. Prognostic value of suPAR in sepsis: a potential tool to support patient management in the Emergency Department
  33. Contribution of SuPAR for patients in a situation of uncertainty downstream of emergencies
  34. One copy in one-pot for rapid and accurate SFTSV testing by LAC12b-2M
  35. Corrigendum
  36. Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperature
  37. Letters to the Editor
  38. Combining the calibrator uncertainty and the long-term measurement uncertainty? A comment to the ISO/TS 20914 guideline
  39. Comparative analysis of plasma p-tau217 immunoassays: challenges for standardization and harmonization
  40. Shift happens: the utility of external quality assessment data in evaluating folate lot changes
  41. Response to: Shift happens: The utility of external quality assessment data in evaluating folate lot changes. doi.org/10.1515/cclm-2025-1569
  42. Innovative closed tube protocol reveals a super critical early preanalytical phase of whole blood glucose stability in routine matrices
  43. Spun citrate samples as a suitable alternative for platelet measurement. Is recollection necessary? A preliminary study
  44. Mass spectrometry reveals limitations of serum immunofixation electrophoresis in monitoring lambda light chain myeloma
  45. A study of the performance of different methods for measuring serum lithium
  46. Congress Abstracts
  47. 47th Annual Conference of the Association for Clinical Biochemists in Ireland (ACBI)
Downloaded on 1.4.2026 from https://www.degruyterbrill.com/document/doi/10.1515/cclm-2025-1336/html
Scroll to top button