Computer aided approximation of flow rate through systemic-pulmonary arterial shunts (SPAS)
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Peter Vennemann
,
Michael Montag
Abstract
The discrimination of flow rates through bronchial arteries that are affected by pathological SPAS today still happens solely qualitatively. A reproducible quantification of flow rates, however, would enable the comprehension of phenomena like the intensified shunt perfusion seen in cases of chronic inflammations or the characterization of SPAS that may cause cardiovascular problems. A computational program is developed, that allows the modeling of individual bronchial arteries on the basis of the information provided by angiography. Angiographic images are available from the standard clinical assessment of SPAS. The flow through continuous and geometrically measurable vessel segments and SPAS is given by the law of Hagen-Poiseuille. The discharge through healthy branches is calculated by means of allometric scaling laws. The simulation results are verified by flow experiments in artificial vessel networks made of glass and PE tubing. The experimental set-up mimics realistic, pulsating pressure and flow conditions. When applied to the artificial vessel networks, the model described herein provides results for the volumetric flow rate that differ from values measured in laboratory experiments by <6%. The computer model is also applied to real angiographic images. Due to inaccuracies during the deduction of the geometry and due to necessary simplifications of the model, we expect significant deviations between calculated and real flow rates in bronchial systems. Nevertheless, the presented method enables the physician to objectively estimate the order of magnitude of volumetric flow through individual SPAS fairly independently from his experience and without the need of measurements additional to the mandatory angiography.
©2012 by Walter de Gruyter Berlin Boston
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- Original Articles
- Comparing measured and simulated wave directions in the left atrium – a workflow for model personalization and validation
- Computer aided approximation of flow rate through systemic-pulmonary arterial shunts (SPAS)
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- Masthead
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Articles in the same Issue
- Original Articles
- Comparing measured and simulated wave directions in the left atrium – a workflow for model personalization and validation
- Computer aided approximation of flow rate through systemic-pulmonary arterial shunts (SPAS)
- Comparison of flow dynamics of Perimount Magna and Magna Ease aortic valve prostheses
- Percutaneous dilational tracheostomy (PDT) and prevention of blood aspiration with superimposed high-frequency jet ventilation (SHFJV) using the tracheotomy-endoscope (TED): results of numerical and experimental simulations
- Development of a test system to analyze different hip fracture osteosyntheses under simulated walking
- Influence of cementless hip stems on femoral cortical strain pattern depending on their extent of porous coating
- A portable magnetic induction measurement system (PIMS)
- Differentiation of enamel lesion activity by vertical reflection intensity – a methodical description
- Masthead
- Masthead
