The HELLP-syndrome; maternal-fetal outcome and follow up of infants
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A. C. Roelofsen
, M. G. van Pampus and J. G. Aarnoudse
Abstract
Objective: To investigate maternal-fetal outcome of infants born after pregnancies complicated by (H)ELLP syndrome. Study design: A retrospective cohort study was performed on patients with the HELLP or ELLP syndrome. Maternal and perinatal complications were recorded. The follow-up period of the infants was at least 18 months. A multivariate regression analysis was done to define the variables mostly contributing to adverse outcome. Results: No maternal deaths occurred. Eighteen infants of the HELLP group and six infants of the ELLP group died; total perinatal mortality was 17.6%. After 18 months four infants had major handicaps, making a total adverse outcome of 22.8%. Statistical analysis shows early gestational age, prolongation of pregnancy and administration of antihypertensive medication as the factors influencing outcome of the infants most. Conclusions: Prolongation of pregnancy contributed to better perinatal outcome, while administration of antihypertensive medication and early gestational age were related to a more unfavorable outcome.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
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- Congress Calendar
Articles in the same Issue
- Telemedicine for antenatal surveillance of high-risk pregnancies with ambulatory and home fetal heart rate monitoring – an update
- The HELLP-syndrome; maternal-fetal outcome and follow up of infants
- Effect of maternal age on blood loss during parturition: a retrospective multivariate analysis of 10,053 cases
- Prenatal medicine related to stress and depressive reactions of pregnant women and their partners
- Accuracy of sonographic estimation of fetal weight before induction of labor in diabetic pregnancies and pregnancies with suspected fetal macrosomia
- Validity of short term variation (STV) in detection of fetal acidemia
- Amikacin alters auditory brainstem conduction time in newborns
- Triplets and quadruplets in Switzerland: comparison with singletons, and evolution over the last decade
- Maternal smoking during pregnancy and appetite control in offspring
- Sequential use of thrombolytic agents for thrombosed mitral valve prosthesis during pregnancy
- Congenital mixed malignant germ cell tumor involving cerebrum and orbit
- Jejunal atresia related to the use of toluidine blue in genetic amniocentesis in twins
- Congress Calendar