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Antithrombotic properties of sulfated wood-derived galactoglucomannans
-
Aleš Doliška
,
Stefan Willför
Published/Copyright:
August 6, 2011
Abstract
Galactoglucomannans (GGMs) are water-soluble polysaccharides released and accumulated in process waters in the production of thermomechanical pulp. The general trend in the forestry industry is moving towards bio-refineries, for example utilizing these hemicelluloses as bioactive substances. At present, there is no industrial use of wood-derived mannans. In this study, GGMs extracted from thermomechanical pulp, as well as further carboxymethyl-ated galactoglucomannans (CM-GGMs), were sulfated to increase their antithrombotic properties. The products were characterized with Fourier transform infrared spectroscopy, nuclear magnetic resonance and capillary electrophoresis. The carbohydrate composition and sulfur amounts were determined. The products’ total charges were determined by polyelectrolyte titrations and their antithrombotic effect was measured based on the activated partial thromboplastin time. The results showed a significant increase in the antithrombotic effect of the sulfated galactoglucomannans from spruce wood and thus a potential new use for wood-derived mannans.
Keywords: activated partial thromboplastin time; anticoagulant; antithrombocity; carboxymethylation; galactoglucomannan; spruce wood; sulfated polysaccharide
Received: 2011-2-7
Accepted: 2011-7-7
Published Online: 2011-08-6
Published in Print: 2012-02-01
©2012 by Walter de Gruyter Berlin Boston
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Articles in the same Issue
- Original Papers
- Oxidative stabilisation of kraft lignin for carbon fibre production
- Antithrombotic properties of sulfated wood-derived galactoglucomannans
- Recycling potential of unbleached and bleached chemical pulps from juvenile and mature wood of Populus deltoides
- Natural and artificial ageing of spruce wood as observed by FTIR-ATR and UVRR spectroscopy
- Characterization of phenolic compounds from inner bark of Betula pendula
- Identification and functional characterization of a sesquiterpene synthase gene from Eleutherococcus trifoliatus
- Microstructure and stiffness of Scots pine (Pinus sylvestris L) sapwood degraded by Gloeophyllum trabeum and Trametes versicolor – Part I: Changes in chemical composition, density and equilibrium moisture content
- Changes in microstructure and stiffness of Scots pine (Pinus sylvestris L) sapwood degraded by Gloeophyllum trabeum and Trametes versicolor – Part II: Anisotropic stiffness properties
- Off-axis Young’s modulus and off-axis shear modulus of wood measured by flexural vibration tests
- Empirical models for radial and tangential fibre width in tree rings of Norway spruce in north-western Europe
- Automatic grain texture analysis using integral transforms
- The fungal resistance of wood modified with glutaraldehyde
- Relative fungal efficacy results from the soil block test with a long incubation period of three commercial copper wood preservatives
- Uneven distribution of preservative in kiln-dried sapwood lumber of Scots pine: Impact of wood structure and resin allocation
- Utilization of surfactants for consolidation of wooden work of art
- Screening for xylanase and β-xylosidase production from wood-inhabiting Penicillium strains for potential use in biotechnological applications
- Short Note
- Furfuryl alcohol impregnation for improved plasticization and fixation during the densification of wood
- Meetings
- Meetings
Keywords for this article
activated partial thromboplastin time;
anticoagulant;
antithrombocity;
carboxymethylation;
galactoglucomannan;
spruce wood;
sulfated polysaccharide
Articles in the same Issue
- Original Papers
- Oxidative stabilisation of kraft lignin for carbon fibre production
- Antithrombotic properties of sulfated wood-derived galactoglucomannans
- Recycling potential of unbleached and bleached chemical pulps from juvenile and mature wood of Populus deltoides
- Natural and artificial ageing of spruce wood as observed by FTIR-ATR and UVRR spectroscopy
- Characterization of phenolic compounds from inner bark of Betula pendula
- Identification and functional characterization of a sesquiterpene synthase gene from Eleutherococcus trifoliatus
- Microstructure and stiffness of Scots pine (Pinus sylvestris L) sapwood degraded by Gloeophyllum trabeum and Trametes versicolor – Part I: Changes in chemical composition, density and equilibrium moisture content
- Changes in microstructure and stiffness of Scots pine (Pinus sylvestris L) sapwood degraded by Gloeophyllum trabeum and Trametes versicolor – Part II: Anisotropic stiffness properties
- Off-axis Young’s modulus and off-axis shear modulus of wood measured by flexural vibration tests
- Empirical models for radial and tangential fibre width in tree rings of Norway spruce in north-western Europe
- Automatic grain texture analysis using integral transforms
- The fungal resistance of wood modified with glutaraldehyde
- Relative fungal efficacy results from the soil block test with a long incubation period of three commercial copper wood preservatives
- Uneven distribution of preservative in kiln-dried sapwood lumber of Scots pine: Impact of wood structure and resin allocation
- Utilization of surfactants for consolidation of wooden work of art
- Screening for xylanase and β-xylosidase production from wood-inhabiting Penicillium strains for potential use in biotechnological applications
- Short Note
- Furfuryl alcohol impregnation for improved plasticization and fixation during the densification of wood
- Meetings
- Meetings
