Article
Licensed
Unlicensed
Requires Authentication
Glycated albumin may be a possible alternative to hemoglobin A1c in diabetic patients with anemia
-
Sollip Kim
,
Sail Chun
Published/Copyright:
June 17, 2011
Abstract
Background: We assessed whether glycated albumin (GA) is a useful glycemic indicator in diabetic patients with anemia who did not undergo dialysis.
Methods: Hemoglobin A1c (HbA1c) and GA were simultaneously measured in 370 diabetic subjects who had not undergone dialysis. The relationship between GA and HbA1c was evaluated in patients with and without anemia.
Results: GA-to-HbA1c ratio was significantly higher (3.3±0.7 vs. 2.8±0.5, p<0.001) and the regression slope between GA and HbA1c was steeper in diabetic patients with than in those without anemia (6.2 vs. 4.2, p<0.001).
Conclusions: HbA1c was underestimated in diabetic patients with anemia than in those without anemia, with the degree of underestimation increasing as glycemic control became poorer. GA may more accurately assess glycemic control in diabetic patients with anemia than HbA1c.
Received: 2011-3-10
Accepted: 2011-5-12
Published Online: 2011-06-17
Published in Print: 2011-10-01
©2011 by Walter de Gruyter Berlin Boston
You are currently not able to access this content.
You are currently not able to access this content.
Articles in the same Issue
- Editorial
- Laboratory medicine: an essential partner in the care of cancer patients
- Reviews
- Circulating tumor cells as emerging tumor biomarkers in breast cancer
- Prognostic, therapeutic and diagnostic potential of microRNAs in non-small cell lung cancer
- Increased plasma concentrations of tumour markers in the absence of neoplasia
- Recent progress and clinical importance on pharmacogenetics in cancer therapy
- Genetics and Molecular Diagnostics
- Genotyping of the hemochromatosis HFE p.H63D and p.C282Y mutations by high-resolution melting with the Rotor-Gene 6000® instrument
- General Clinical Chemistry and Laboratory Medicine
- Mapping point-of-care performance using locally-smoothed median and maximum absolute difference curves
- The use of inflammatory markers as a method for discharging patients post hip or knee arthroplasty
- Significant elevation of plasma pentraxin 3 in patients with pelvic inflammatory disease
- Combined effects of coffee consumption and serum γ-glutamyltransferase on serum C-reactive protein in middle-aged and elderly Japanese men and women
- Multicentre comparison of free thyroid hormones immunoassays: the Immunocheck study
- Comparative evaluation of capillary zone electrophoresis and HPLC in the determination of carbohydrate-deficient transferrin
- Determinants of blood levels of some thrombogenic biomarkers in healthy Arab adolescent subjects
- Analytical performance of a multiplexed, bead-based cytokine detection system in small volume samples
- Diagnostic utility of a soluble cytokeratin 18 assay for gastrointestinal graft-vs.-host disease detection
- Cancer Diagnostics
- The correlation between zinc and insulin-like growth factor 1 (IGF-1), its binding protein (IGFBP-3) and prostate-specific antigen (PSA) in prostate cancer
- Differential expression of CDC25 phosphatases splice variants in human breast cancer cells
- Serum APRIL, a potential tumor marker in pancreatic cancer
- Clinical significance of pleural effusion mesothelin in malignant pleural mesothelioma
- Infectious Diseases
- New serum biomarkers for detection of tuberculosis using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry
- Cardiovascular Diseases
- Association of a functional polymorphism in the MMP7 gene promoter with susceptibility to vulnerable carotid plaque in a Han Chinese Population
- Diabetes
- Glycated albumin may be a possible alternative to hemoglobin A1c in diabetic patients with anemia
- A simple micro-photometric method for urinary iodine determination
- Letters to the Editor
- Clinically needed sensitivity for very low levels of Factor XIII: not yet proven for a new functional assay
- Apolipoprotein A5-12238 T>C gene polymorphism and risk factors for metabolic syndrome in the Guo Shan Yao and the Han populations
- Congress Abstracts
- 10.1515/CCLM.2011.738
- 1st National Congress of Laboratory Medicine
Articles in the same Issue
- Editorial
- Laboratory medicine: an essential partner in the care of cancer patients
- Reviews
- Circulating tumor cells as emerging tumor biomarkers in breast cancer
- Prognostic, therapeutic and diagnostic potential of microRNAs in non-small cell lung cancer
- Increased plasma concentrations of tumour markers in the absence of neoplasia
- Recent progress and clinical importance on pharmacogenetics in cancer therapy
- Genetics and Molecular Diagnostics
- Genotyping of the hemochromatosis HFE p.H63D and p.C282Y mutations by high-resolution melting with the Rotor-Gene 6000® instrument
- General Clinical Chemistry and Laboratory Medicine
- Mapping point-of-care performance using locally-smoothed median and maximum absolute difference curves
- The use of inflammatory markers as a method for discharging patients post hip or knee arthroplasty
- Significant elevation of plasma pentraxin 3 in patients with pelvic inflammatory disease
- Combined effects of coffee consumption and serum γ-glutamyltransferase on serum C-reactive protein in middle-aged and elderly Japanese men and women
- Multicentre comparison of free thyroid hormones immunoassays: the Immunocheck study
- Comparative evaluation of capillary zone electrophoresis and HPLC in the determination of carbohydrate-deficient transferrin
- Determinants of blood levels of some thrombogenic biomarkers in healthy Arab adolescent subjects
- Analytical performance of a multiplexed, bead-based cytokine detection system in small volume samples
- Diagnostic utility of a soluble cytokeratin 18 assay for gastrointestinal graft-vs.-host disease detection
- Cancer Diagnostics
- The correlation between zinc and insulin-like growth factor 1 (IGF-1), its binding protein (IGFBP-3) and prostate-specific antigen (PSA) in prostate cancer
- Differential expression of CDC25 phosphatases splice variants in human breast cancer cells
- Serum APRIL, a potential tumor marker in pancreatic cancer
- Clinical significance of pleural effusion mesothelin in malignant pleural mesothelioma
- Infectious Diseases
- New serum biomarkers for detection of tuberculosis using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry
- Cardiovascular Diseases
- Association of a functional polymorphism in the MMP7 gene promoter with susceptibility to vulnerable carotid plaque in a Han Chinese Population
- Diabetes
- Glycated albumin may be a possible alternative to hemoglobin A1c in diabetic patients with anemia
- A simple micro-photometric method for urinary iodine determination
- Letters to the Editor
- Clinically needed sensitivity for very low levels of Factor XIII: not yet proven for a new functional assay
- Apolipoprotein A5-12238 T>C gene polymorphism and risk factors for metabolic syndrome in the Guo Shan Yao and the Han populations
- Congress Abstracts
- 10.1515/CCLM.2011.738
- 1st National Congress of Laboratory Medicine
