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New creatinine sensor for point-of-care testing of creatinine meets the National Kidney Disease Education Program guidelines
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Anne Skurup
Veröffentlicht/Copyright:
30. Juli 2007
Abstract
Addition of the measurement of creatinine concentration in whole blood on the ABL837 FLEX blood gas analyzer (Radiometer Medical ApS, Copenhagen, Denmark) allows fast and reliable reporting of creatinine in point-of-care testing (POCT). The new creatinine sensor follows the international recommendations of the National Kidney Disease Education Program Laboratory Working Group as of January 2006 with respect to acceptable performance, reference method and traceability. Validation tests show that the creatinine sensor has excellent performance and thus has the potential to change the poor track record of creatinine testing in plasma and whole blood in both the clinical laboratory and POCT. This article describes the clinical needs and the methods currently available for creatinine measurement and presents performance tests carried out by the manufacturer.
Clin Chem Lab Med 2008;46:3–8.
Keywords: creatinine; glomerular filtration rate (GFR); National Kidney Disease Education Program (NKDEP) standardization; point-of-care testing
Received: 2007-1-8
Accepted: 2007-1-31
Published Online: 2007-07-30
Published in Print: 2008-01-01
©2008 by Walter de Gruyter Berlin New York
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Artikel in diesem Heft
- Editorial
- Improving healthcare through advances in point-of-care technologies
- Review
- New creatinine sensor for point-of-care testing of creatinine meets the National Kidney Disease Education Program guidelines
- Original Papers
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- Comparative study of calculated and measured total carbon dioxide
- Letter to the Editor
- Performance of immunofluorometric point-of-care assays for free pregnancy-associated plasma protein A detection in whole blood samples
- Guidelines and Recommendations
- IFCC Guideline for sampling, measuring and reporting ionized magnesium in plasma
- Reviews
- Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics
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- Validation and Outcome Studies
- Analytical evaluation of the Optium Xido blood glucose meter
- Letters to the Editor
- New biomarkers of myocardial injury and assessment of cardiac toxicity during preparative regimen and hematopoietic cell transplantation in acute leukemia
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Schlagwörter für diesen Artikel
creatinine;
glomerular filtration rate (GFR);
National Kidney Disease Education Program (NKDEP) standardization;
point-of-care testing
Artikel in diesem Heft
- Editorial
- Improving healthcare through advances in point-of-care technologies
- Review
- New creatinine sensor for point-of-care testing of creatinine meets the National Kidney Disease Education Program guidelines
- Original Papers
- Performance of a multi-profile critical care testing analyzer
- Comparative study of calculated and measured total carbon dioxide
- Letter to the Editor
- Performance of immunofluorometric point-of-care assays for free pregnancy-associated plasma protein A detection in whole blood samples
- Guidelines and Recommendations
- IFCC Guideline for sampling, measuring and reporting ionized magnesium in plasma
- Reviews
- Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics
- The entero-insular axis: implications for human metabolism
- Genetics and Molecular Diagnostics
- Functional polymorphisms in the promoter of the matrix metalloproteinase-9 (MMP-9) gene are not linked with significant plasma MMP-9 variations in healthy subjects
- Genetic profiling in healthy subjects from the Stanislas cohort based on 24 polymorphisms: effects on biological variables
- Relationship between methionine synthase, methionine synthase reductase genetic polymorphisms and deep vein thrombosis among South Indians
- Simultaneous genotyping of the three lactose tolerance-linked polymorphisms LCT –13907C>G, LCT –13910C>T and LCT –13915T>G with Pyrosequencing™ technology
- A new high-throughput screening method for the detection of chronic lymphatic leukemia and myelodysplastic syndrome
- General Clinical Chemistry and Laboratory Medicine
- Saliva analysis by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF/MS): from sample collection to data analysis
- Mechanism of sodium loss with muscle sodium deficiency in sodium supplemented and unsupplemented subjects during hypokinesia
- Increased levels of 8-hydroxydeoxyguanosine and its relationship with lipid peroxidation and antioxidant vitamins in lung cancer
- Lipid peroxidation in stroke patients
- Resistin is present in human breast milk and it correlates with maternal hormonal status and serum level of C-reactive protein
- Waist-to-hip ratio correlates with homocysteine levels in male patients with coronary artery disease
- Isoenzymes of N-acetyl-β-hexosaminidase in human pleomorphic adenoma and healthy salivary glands: a preliminary study
- The in vivo and in vitro effects of L-carnitine supplementation on the erythrocyte membrane acetylcholinesterase, Na+, K+-ATPase and Mg2+-ATPase activities in basketball players
- Validation and Outcome Studies
- Analytical evaluation of the Optium Xido blood glucose meter
- Letters to the Editor
- New biomarkers of myocardial injury and assessment of cardiac toxicity during preparative regimen and hematopoietic cell transplantation in acute leukemia
- Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome
