Westgard multirule for calculated laboratory tests
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Abdurrahman Coskun
Abstract
Background: In clinical laboratories, many test results such as low-density lipoprotein (LDL)-cholesterol can be calculated using the results of specifically measured tests. However, quality control programs deal only with measured tests and there is no adequate quality assessment procedure for calculated tests. I aimed to apply the Westgard multirule to calculated tests as a part of routine quality procedures.
Methods: I prepared a Levey-Jennings chart for calculated tests and all their measured components (Equation chart) and then applied the Westgard multirule to these tests.
Results: Applying the Westgard multirule to calculated LDL-cholesterol (and other calculated tests) was simple, and increased the reliability of the results of the calculated tests.
Conclusions: Checking the reliability of only measured tests by quality control procedures before reporting patient results may be inadequate. Applying the Westgard multirule to calculated tests as part of total quality management will increase the reliability of test results.
Clin Chem Lab Med 2006;44:1183–7.
References
1. Coskun A. The reliability of calculated laboratory tests. Clin Chem Lab Med 2005; 43:880–2.10.1515/CCLM.2005.148Search in Google Scholar PubMed
2. Coskun A. Modified Levey-Jennings charts for calculated laboratory tests. Clin Chem Lab Med 2006; 44:387–90.10.1515/CCLM.2006.066Search in Google Scholar PubMed
3. Coskun A. Six sigma and calculated laboratory tests. Clin Chem 2006; 52:770–1.10.1373/clinchem.2005.064311Search in Google Scholar PubMed
4. Rifai N, Warnick GR. Lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors. In: Burtis CA, Ashwood ER, Bruns DE, editors. Tietz textbook of clinical chemistry and molecular diagnostics. St. Louis, MO: Elsevier Saunders Inc., 2006:903–81.Search in Google Scholar
5. Westgard JO, Barry PL, Hunt MR, Groth T. A multirule Shewhart chart for quality control in clinical chemistry. Clin Chem 1981; 27:493–501.10.1093/clinchem/27.3.493Search in Google Scholar
©2006 by Walter de Gruyter Berlin New York
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- Apolipoprotein B gene 3′VNTR polymorphism: association with plasma lipids and coronary heart disease in Han Chinese
- Paraoxonase-1 (PON1) activity, but not PON1Q192R phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population
- A modified method of prothrombin time/International Normalised Ratio determination in capillary blood and monitoring oral anticoagulant therapy
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