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Recommendations for the Routine Use of Pancreatic Amylase Measurement instead of Total Amylase for the Diagnosis and Monitoring of Pancreatic Pathology
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Mauro Panteghini
Published/Copyright:
June 1, 2005
Abstract
This document reviews the scientific evidence expected to persuade clinical laboratories to substitute pancreatic amylase measurement for total amylase in cases of suspected pancreatic pathology. A substantial evidence is now available to support such change. The measurement of pancreatic amylase in serum is: 1. more sensitive and specific for the detection of pancreatic tissue damage than that of the total enzyme activity, 2. easy and quick to perform in emergency conditions, 3. analytically precise in relation to its clinical application, 4. suitable for easy transfer and comparison of results from different care delivery units, and 5. characterized by welldefined decision limits for the diagnosis of acute pancreatitis.
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Published Online: 2005-06-01
Published in Print: 2002-03-01
Copyright © 2002 by Walter de Gruyter GmbH & Co. KG
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- Bovine Spongiform Encephalopathy: Are the Cows Mad or Full of Carbohydrates?
- Plasma Total Antioxidant Capacity in Hemodialyzed Patients and Its Relationships to other Biomarkers of Oxidative Stress and Lipid Peroxidation
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- Renal Function Exerts only a Minor Influence on High Plasma Homocysteine Concentrations in Patients with Acute Coronary Syndromes
- Changes of Biochemical Bone Markers during the Menopausal Transition
- Blood Sampling for Biochemical Analysis from Central Venous Catheters: Minimizing the Volume of Discarded Blood
- Experience with External Quality Assessment of Drugs of Abuse Testing in the Lombardy Region in Italy
- Reference Intervals for Thyroid Hormones on the Architect Analyser
- Intermethod Variation in Serum Carcinoembryonic Antigen (CEA) Measurement. Fresh Serum Pools and Control Materials Compared
- Turn-Around Time for Chemical and Endocrinology Analyzers Studied Using Simulation
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