Functional Consequences of Cathepsin L Deficiency in Human Lung Epithelial Cells

Articles in the same Issue

1. The International Proteolysis Society (IPS): A Society for Proteolysis, Proteases and Protease Inhibitors
2. Proteases and Their Inhibitors: Traditional Research Subjects in the Munich Area
3. Apoptotic Pathways: Involvement of Lysosomal Proteases
4. Human Tissue Kallikreins: A New Enzymatic Cascade Pathway?
5. Discovery of Chemokine Substrates for Matrix Metalloproteinases by Exosite Scanning: A New Tool for Degradomics
6. Novel Secretory Vesicle Serpins, Endopin 1 and Endopin 2: Endogenous Protease Inhibitors with Distinct Target Protease Specificities
7. Extracellular Proteases of Staphylococcus spp.
8. Secreted Aspartic Proteases as Virulence Factors of Candida Species
9. Triple-Helical Peptide Analysis of Collagenolytic Protease Activity
10. Phage Display Substrate: A Blind Method for Determining Protease Specificity
11. Evolution of Placental Proteases
12. Factor VII Activating Protease (FSAP): A Novel Protease in Hemostasis
13. Cold-Adapted and Mesophilic Brachyurins
14. The Role of Dipeptidyl Peptidase IV (DP IV) Enzymatic Activity in T Cell Activation and Autoimmunity
15. Biochemical Features, Molecular Biology and Clinical Relevance of the Human 15-Domain Serine Proteinase Inhibitor LEKTI
16. Interaction of Plasminogen Activator Inhibitor Type-1 (PAI-1) with Vitronectin (Vn): Mapping the Binding Sites on PAI-1 and Vn
17. Structure-Function Relationship of Bromelain Isoinhibitors from Pineapple Stem
18. Structural Basis for the Processive Protein Degradation by Tricorn Protease
19. Zinc Ligands in an Astacin Family Metalloprotease Meprin A
20. Probing the Active Sites and Mechanisms of Rat Metalloproteases Meprin A and B
21. (R)-3-Amidinophenylalanine-Derived Inhibitors of Factor Xa with a Novel Active-Site Binding Mode
22. Inhibition of Arginine Gingipains (RgpB and HRgpA) with Benzamidine Inhibitors: Zinc Increases Inhibitory Potency
23. Cathepsin B Stability, But Not Activity, Is Affected in Cysteine:Cystine Redox Buffers
24. Inhibition of Mammalian Legumain by Michael Acceptors and AzaAsn-Halomethylketones
25. Role of the Prosegment of Fasciola hepatica Cathepsin L1 in Folding of the Catalytic Domain
26. Roles for Arg- and Lys-Gingipains in the Disruption of Cytokine Responses and Loss of Viability of Human Endothelial Cells by Porphyromonas gingivalis Infection
27. Aberrant Expression of Serpin Squamous Cell Carcinoma Antigen 2 in Human Tumor Tissues and Cell Lines: Evidence of Protection from Tumor Necrosis Factor-Mediated Apoptosis
28. Endosomal-Lysosomal Proteolysis Mediates Death Signalling by TNFα, Not by Etoposide, in L929 Fibrosarcoma Cells: Evidence for an Active Role of Cathepsin D
29. Anti-Inflammatory Effect of Pre-Elafin in Lipopolysaccharide-Induced Acute Lung Inflammation
30. The 26S Proteasome Rpn10 Gene Encoding Splicing Isoforms: Evolutional Conservation of the Genomic Organization in Vertebrates
31. Reverse Genetic Analysis of the Caenorhabditis elegans 26S Proteasome Subunits by RNA Interference
32. Purification and Characterization of the 20S Proteasome from Ostrich Skeletal Muscle
33. Identification of a Signal Transduction Pathway That Regulates MMP-9 mRNA Expression in Glomerular Injury
34. Modulation of the Endosomal and Lysosomal Distribution of Cathepsins B, L and S in Human Monocytes/Macrophages
35. Characterization of Novel Anti-Cathepsin W Antibodies and Cellular Distribution of Cathepsin W in the Gastrointestinal Tract
36. Functional Consequences of Cathepsin L Deficiency in Human Lung Epithelial Cells
37. Determination of Cathepsin B Expression May Offer Additional Prognostic Information for Ovarian Cancer Patients
38. CA-074, But Not Its Methyl Ester CA-074Me, Is a Selective Inhibitor of Cathepsin B within Living Cells
39. Trypsin Mutants for Structure-Based Drug Design: Expression, Refolding and Crystallisation