Welcome address

Chapters in this book

1. Frontmatter 1
2. Welcome address 5
3. Contents 7
4. Introduction 9
5. Antiandrogen therapy for signs of androgenization: an overview 15
6. I. Pharmacology and physiology
7. Pharmacological aspects of cyproterone acetate 23
8. Pharmacokinetics of cyproterone acetate and ethinyl estradiol in smoking and non-smoking women during treatment with Diane-35 41
9. Ovulation inhibitory effect of SH B 209 AE (Diane-35)—a new antiandrogen-estrogen combination 51
10. A study to investigate the maintenance of ovulation inhibition when patients switch over from Diane to Diane-35 59
11. Effect of a new antiandrogen-estrogen sub-fifty combination on the endometrium 69
12. II. Polycystic ovary syndrome
13. Endocrinological and clinical findings on the therapy with Diane-35 in polycystic ovary syndrome 83
14. Discussion 93
15. III. Effects on the haemostatic system
16. Longitudinal study on the effects of a cyproterone acetate and ethinyl estradiol combination on haemostasis 101
17. Haemorheological effects of Diane-35 and Microgynon®—Preliminary results of a double blind study 109
18. Antiandrogen treatment in women with acne: a controlled trial 117
19. IV Special aspects
20. Clinical assessment of two antiandrogen treatments, cyproterone acetate combined with ethinyl estradiol and spironolactone in hirsutism 133
21. Treatment of severe androgenization symptoms with Diane and intramuscularly applied cyproterone acetate (Androcur Depot) 139
22. One-year experience with a new oral contraceptive using natural estradiol and cyproterone acetate 153
23. Discussion 159
24. V. Metabolic and clinical aspects
25. Clinical and metabolic effects of a new estrogenantiandrogen low dose combination 167
26. Effects of cyproterone acetate on serum lipoproteins when administered alone and in combination with ethinyl estradiol 175
27. Clinical, metabolic and endocrine effects of long term use of a cyproterone acetate and ethinyl estradiol combination in hyperandrogenized women 183
28. Cyproterone acetate versus levonorgestrel combined with ethinyl estradiol in the treatment of acne : results of a multi-center study 191
29. Comparison of Diane-35 with Neo-Eunomin from the dermatological viewpoint 197
30. A double blind comparative study of tetracycline and Diane, alone and in combination in the treatment of acne 207
31. The comparative efficacy and safety of Diane- 35 versus Diane-50 in the treatment of moderate to severe acne and seborrhea: preliminary results 217
32. Results of an extended open phase m study with Diane-35 229
33. Discussion 238
34. Closing remarks 242
35. List of first-mentioned contributors 243