Animal Cell Biotechnology
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Edited by:
Hansjörg Hauser
About this book
This book introduces fundamental principles and practical application of techniques used in the scalable production of biopharmaceuticals with animal cell cultures. A broad spectrum of subjects relevant to biologics production and manufacturing are reviewed, including the generation of robust cell lines, a survey of functional genomics for a better understanding of cell lines and processes, as well as advances in regulatory compliant upstream and downstream development. The book is an essential reference for all those interested in translational animal cell-based pharmaceutical biotechnology.
- Animal cells for the industrial manufacturing of recombinant proteins and virus-based biologics
- Includes latest scientific and technological aspects from gene(s) to warehouse
- Full color illustrations
Author / Editor information
Hansjörg Hauser, Helmholtz Centre for Infection Research, Braunschweig; Roland Wagner, Rentschler Biotechnologie GmbH, Laupheim
Supplementary Materials
Topics
Publicly Available Download PDF |
I |
Requires Authentication Unlicensed Licensed Download PDF |
V |
Publicly Available Download PDF |
VII |
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IX |
1. Introduction
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Roland Wagner and Hansjörg Hauser Requires Authentication Unlicensed Licensed Download PDF |
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2. Cell Lines
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Christoph Lipps, Tobias May and Dagmar Wirth Requires Authentication Unlicensed Licensed Download PDF |
11 |
Florian M. Wurm Requires Authentication Unlicensed Licensed Download PDF |
38 |
Ingo Jordan and Volker Sandig Requires Authentication Unlicensed Licensed Download PDF |
60 |
Roderick A. F. MacLeod and Hans G. Drexler Requires Authentication Unlicensed Licensed Download PDF |
87 |
Wilhelm G. Dirks and Cord C. Uphoff Requires Authentication Unlicensed Licensed Download PDF |
102 |
3. Genetic Engineering of Cells
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Hitto Kaufmann Requires Authentication Unlicensed Licensed Download PDF |
115 |
Takeshi Omasa and Kyoungho Lee Requires Authentication Unlicensed Licensed Download PDF |
127 |
David Ausländer and Martin Fussenegger Requires Authentication Unlicensed Licensed Download PDF |
144 |
Natascha Kruse, Shawal Spencer and Dagmar Wirth Requires Authentication Unlicensed Licensed Download PDF |
173 |
Hans Henning von Horsten, Karsten Winkler and Volker Sandig Requires Authentication Unlicensed Licensed Download PDF |
216 |
4. Engineering of the Product
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Sandra V. Bennun, Kelley M. Heffner, Emily Blake, Andrew Chung and Michael J. Betenbaugh Requires Authentication Unlicensed Licensed Download PDF |
247 |
Lore Florin, Sören K. Rasmussen, Torben P. Frandsen and Anne B. Tolstrup Requires Authentication Unlicensed Licensed Download PDF |
280 |
5. Basic Aspects of Animal Cell Cultivation
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Venkata Tayi and Michael Butler Requires Authentication Unlicensed Licensed Download PDF |
301 |
Karina Brinkrolf, Raimund Hoffrogge, Matthias Hackl, Andreas Tauch, Martina Baumann, Thomas Noll, Alexander Goesmann, Alfred Pühler and Nicole Borth Requires Authentication Unlicensed Licensed Download PDF |
326 |
Claudia Altamirano, Julio Berrios and Mauricio Vergara Requires Authentication Unlicensed Licensed Download PDF |
368 |
6. Upstream and Downstream Process Technology
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Detlef Eisenkraetzer Requires Authentication Unlicensed Licensed Download PDF |
389 |
Natalia Ceaglio, Mariela Bollati-Fogolín, Marcos Oggero, Marina Etcheverrigaray and Ricardo Kratje Requires Authentication Unlicensed Licensed Download PDF |
427 |
Weiwei Hu and Kelly Wiltberger Requires Authentication Unlicensed Licensed Download PDF |
455 |
Nuno Fontes, Ruoheng Zhang and Jens H. Vogel Requires Authentication Unlicensed Licensed Download PDF |
489 |
7. Monitoring and Control of Processes and Products
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John Paul Smelko, Thomas Ryll and Dethardt Müller Requires Authentication Unlicensed Licensed Download PDF |
523 |
Amy Hong Que, Yang Wang and Steven Ziyi Kan Requires Authentication Unlicensed Licensed Download PDF |
571 |
Vijay Janakiraman, Matthew Westoby and Lynn Conley Requires Authentication Unlicensed Licensed Download PDF |
598 |
8. Pharmaceutical Aspects of Biologics from Animal Cell Culture Processes
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Balder Rebmann, Peter van Hoogevest, Matias Zurbriggen and Wilfried Weber Requires Authentication Unlicensed Licensed Download PDF |
649 |
Requires Authentication Unlicensed Licensed Download PDF |
693 |
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Manufacturer information:
Walter de Gruyter GmbH
Genthiner Straße 13
10785 Berlin
productsafety@degruyterbrill.com