Article
Publicly Available
Preorganization in biological systems: Are conformational constraints worth the energy?
-
Stephen F. Martin
Published/Copyright:
January 1, 2009
Published Online: 2009-01-01
Published in Print: 2007-01-01
© 2013 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Preface
- Synthetic studies toward shellfish toxins containing spiroacetal units
- Recent results toward the stereoselective synthesis of biologically active natural products
- Natural products with taxol-like anti-tumor activity: Synthetic approaches to eleutherobin and dictyostatin
- Conjugate systems in the construction of heterocycles and quaternary stereocenters
- Preorganization in biological systems: Are conformational constraints worth the energy?
- Functional phosphorus-based π-conjugated systems: Structural diversity without multistep synthesis
- Enantioenriched cyanohydrin O-phosphates: Synthesis and applications as chiral building blocks
- Boron: A key element in radical reactions
- Asymmetric catalysis in aqueous media
- Modified mesoporous materials as Pd scavengers and catalyst supports
- Control of regio- and stereoselectivity in electrophilic addition reactions of allenes
- Widening the usefulness of epoxides and aziridines in synthesis
- Biomimetic synthesis via polyepoxide cyclizations
Keywords for this article
enzyme inhibitors;
ligand preorganization;
molecular recognition;
protein-ligand interactions;
structure;
thermodynamics
Articles in the same Issue
- Preface
- Synthetic studies toward shellfish toxins containing spiroacetal units
- Recent results toward the stereoselective synthesis of biologically active natural products
- Natural products with taxol-like anti-tumor activity: Synthetic approaches to eleutherobin and dictyostatin
- Conjugate systems in the construction of heterocycles and quaternary stereocenters
- Preorganization in biological systems: Are conformational constraints worth the energy?
- Functional phosphorus-based π-conjugated systems: Structural diversity without multistep synthesis
- Enantioenriched cyanohydrin O-phosphates: Synthesis and applications as chiral building blocks
- Boron: A key element in radical reactions
- Asymmetric catalysis in aqueous media
- Modified mesoporous materials as Pd scavengers and catalyst supports
- Control of regio- and stereoselectivity in electrophilic addition reactions of allenes
- Widening the usefulness of epoxides and aziridines in synthesis
- Biomimetic synthesis via polyepoxide cyclizations