Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi

Articles in the same Issue

1. Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems
2. Antiangiogenic heparin-derived heparan sulfate mimics
3. Semisynthesis and degradation of the tubulin inhibitors epothilone and tubulysin
4. Synthesis of carbohydrate-based antibiotics
5. DNA minor-groove binders. Design, synthesis and biological evaluation of ligands structurally related to CC-1065, distamycin, and anthramycin
6. HIV-1 integrase inhibitors that block HIV-1 replication in infected cells. Planning synthetic derivatives from natural products
7. New and old challenges in total synthesis. From concept to practice
8. Chemoenzymatic methods for the enantioselective preparation of sesquiterpenoid natural products from aromatic precursors
9. Total synthesis of (­)-clavukerin A
10. Progress in fumagillin synthesis
11. Total syntheses of 11-deoxytetrodotoxin and 8,11-dideoxytetrodotoxin
12. Biomimetic approach toward the stereoselective synthesis of acetogenins
13. Microencapsulated methylrhenium trioxide (MTO)/H2O2 systems for the oxidation of cardanol derivatives
14. Enantioselective synthesis and biological evaluation of a-hydroxylated lactone lignans
15. Stereocontrolled construction of conformationally constrained and rigid bis(a-amino acid) derivatives
16. Stereochemical analysis of natural products. Approaches relying on the combination of NMR spectroscopy and computational methods
17. Exploitation of proteomics strategies in protein structure-function studies
18. Prion protein allotype profiling by mass spectrometry
19. Toxins from Adriatic blue mussels. A decade of studies
20. Bioactive macrolides and polyketides from marine dinoflagellates
21. Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi
22. Chemical studies on plant leaf movement controlled by a biological clock
23. Structural flexibility of hyaluronan oligomers as probed by molecular modelling
24. Functional genomics approach to the study of triterpene biosynthesis
25. Mevalonate-independent methylerythritol phosphate pathway for isoprenoid biosynthesis. Elucidation and distribution
26. Biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum
27. The deoxyxylulose phosphate pathway of isoprenoid biosynthesis. Discovery and function of the ispDEFGH genes and their cognate enzymes
28. Natural and totally synthetic receptors in the innovative design of HPLC chiral stationary phases
29. Combination of enzymatic procedures with multicomponent condensations