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How are opioids used in Norway? Persistent use, utilization of depot formulation and age profile in non-palliation patients
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Kristian Svendsen
Veröffentlicht/Copyright:
1. Juli 2010
Objectives
The extent of persistent opioid use in Norway is unknown. We have studied how many persistent opioid users there are in Norway, whether they use long- or short acting opioids and the age distribution of these patients.
Methods
We have used the Norwegian prescription database containing all drugs dispensed since 2004. We have created three definitions of persistent opioid use corresponding to different clinical settings. The tree definitions are based on amount of opioid dispensed, frequency of dispensing and distribution of dispensing throughout the year. We will present 2008 data of non cancer patients. These three patient groups are: (1) Wide: opioids are used on and off throughout the year in at least half the days. (2) Intermediary: opioids are used on average every day throughout the year. (3) Strict: opioids are used continuously every day in high doses throughout the year.
Results
There are 421,724 non-persistent opioid users in 2008. There are 24,462, 14,132 and 6547 in settings 1, 2 and 3 respectively. These numbers account for 8.90, 0.52, 0.30 and 0.14% of the Norwegian population. Together the three groups of patients account for 45,141 persistent opioid users (0.95% of the population). The percentage of users who use mainly long acting opioids (>80%) is; 2.7%, 9.7%, 16.0% and 36.9% for non-persistent users, groups 1, 2 and 3 respectively. The age of opioid users was studied. The percentage under 30 years old was 14.6%, 2.3%, 2.1% and 3.3% for non-persistent users and groups 1, 2 and 3 respectively. Over 60 years old the percentages are 36.0%, 53.0%, 46.1% and 33.1% respectively.
Conclusion
Less than 10% of people using opioids in 2008 are persistent users. Young people use opioids less persistently. There is a correlation between increased degree of persistence and increased use of long acting opioids.
Published Online: 2010-07-01
Published in Print: 2010-07-01
© 2010 Scandinavian Association for the Study of Pain
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