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SNAPPE-II application in newborns with very low birth weight: evaluation of adverse outcomes in severe placental dysfunction
-
Paulo Roberto Nassar Carvalho
,
Maria Elizabeth Lopes Moreira
Veröffentlicht/Copyright:
11. Februar 2011
Abstract
Aim: The aim of this study was to evaluate the ability of the admission Score for Neonatal Acute Physiology – Perinatal Extension-II (SNAPPE-II) to predict adverse outcome among premature very low birth weight (BW) infants with abnormal Doppler blood flow in the uterus secondary to severe placental insufficiency of early onset.
Methods: A total of 86 neonates, weighing between 360 and 1498 g, were studied. Descriptive statistics of the population were reported. The areas under the receiver operating characteristics curves for the SNAPPE-II were calculated. The calibration of the model was assessed using the technique of Hosmer-Lemeshow. Adverse outcome was defined as mortality or the development of the following diagnoses: (1) periventricular-intraventricular hemorrhage (PIH); (2) retinopathy of prematurity stage 3 or 4; (3) periventricular leukomalacia; (4) bronchopulmonary dysplasia; (5) necrotizing enterocolitis (NEC).
Results: The SNAPPE-II area under curve was 0.86 (95% CI: 0.78–0.94) for mortality and 0.76 (95% CI: 0.65–0.86) for the prediction of adverse outcomes. Analyzing each morbidity variable, the SNAPPE-II AUC varied between 0.51 for NEC and 0.72 for PIH.
Conclusion: SNAPPE-II shows accuracy in the predic-tion of adverse outcome for this highly selective group of very low BW infants compromised by severe placental insufficiency.
Received: 2010-6-10
Revised: 2010-9-19
Accepted: 2010-9-24
Published Online: 2011-02-11
Published Online: 2011-02-11
Published in Print: 2011-05-01
©2011 by Walter de Gruyter Berlin New York
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- Does prenatal antibiotic therapy compromise the diagnosis of early-onset infection and management of the neonate?
- SNAPPE-II application in newborns with very low birth weight: evaluation of adverse outcomes in severe placental dysfunction
- SHORT COMMUNICATION
- Lamellar bodies: platelet channel particles as predictors of respiratory distress syndrome (RDS) and of transient tachypnea of the newborn
- Intrahepatic and adrenal hemorrhage as a rare cause of neonatal anemia
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- Calendar
- Congress Calendar
Schlagwörter für diesen Artikel
Doppler;
neonatal morbidity;
premature;
severity score;
very low birth weight
Artikel in diesem Heft
- Publisher’s Note
- Publisher’s Note
- EDITORIAL
- Problems in prevention of preterm birth – regrettable contradictions
- REVIEW ARTICLES
- Listeriosis in human pregnancy: a systematic review
- Prevention of prematurity by single embryo transfer
- ORIGINAL ARTICLES - OBSTETRICS
- Effect of prior cesarean delivery on neonatal outcomes
- Amniotic lamellar body counts can predict the occurrence of respiratory distress syndrome as well as transient tachypnea of the newborn (TTN)
- Spectrum of cardiovascular findings during pregnancy and parturition at a tertiary referral center
- Risk groups and maternal-neonatal complications of preeclampsia – Current results from the national German Perinatal Quality Registry
- miRNA expression profiling in formalin-fixed and paraffin-embedded placental tissue samples from pregnancies with severe preeclampsia
- Genetic polymorphisms of killer cell immunoglobulin-like receptor 3DL2 in preeclampsia
- Addressing concerns about cisplatin application during pregnancy
- Retinol-binding protein-4 is decreased in patients with preeclampsia in comparison with normal pregnant women
- Somatic classification of neonates based on birth weight, length, and head circumference: quantification of the effects of maternal BMI and smoking
- Prediction of successful labor induction by evaluation of maternal symptoms at an early stage of the misoprostol induction protocol
- ORIGINAL ARTICLES - FETUS
- Increased nuchal translucency is associated with large for gestational age neonates in singleton pregnancies
- ORIGINAL ARTICLES - NEWBORN
- Predicting mortality in infants with persistent pulmonary hypertension of the newborn with the Score for Neonatal Acute Physiology-Version II (SNAP-II) in Thai neonates
- Neonatal outcome of preterm discordant twins
- Effects of delayed umbilical cord clamping on peripheral blood hematopoietic stem cells in premature neonates
- In utero exposure to Ureaplasma spp. is associated with increased rate of bronchopulmonary dysplasia and intraventricular hemorrhage in preterm infants
- Does prenatal antibiotic therapy compromise the diagnosis of early-onset infection and management of the neonate?
- SNAPPE-II application in newborns with very low birth weight: evaluation of adverse outcomes in severe placental dysfunction
- SHORT COMMUNICATION
- Lamellar bodies: platelet channel particles as predictors of respiratory distress syndrome (RDS) and of transient tachypnea of the newborn
- Intrahepatic and adrenal hemorrhage as a rare cause of neonatal anemia
- Subcutaneous fat distribution in small for gestational age newborns
- Calendar
- Congress Calendar
