National survey on delta checks in clinical laboratories in China
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Shukang He
Abstract
Background
This study aimed to understand the status quo of delta checks in Chinese clinical laboratories through a nationwide online survey.
Methods
The survey was divided into two parts. The first part was a general situation survey in which clinical laboratories had to provide information about the laboratories, including delta checks used. In the second part, clinical laboratories were asked to record the delta check alerts generated in their laboratories from June 1st, 2019 to June 30th, 2019.
Results
The most frequently used analytes in delta checks were potassium (K), glucose (Glu), creatinine (Cre) for clinical chemistry and hemoglobin (Hgb), platelet (PLT) count and white blood cell (WBC) count for clinical hematology. The median maximum time interval between specimens for all analytes was 5 days. The most commonly used delta check calculation modes in Chinese clinical laboratories were percentage change and absolute change. K and Hgb were the analytes most involved in clinical chemistry and clinical hematology delta check alerts. The most common causes of delta check alerts were that the patients had received treatment, which was followed by the change in the patient’s physiological state and interference from hemolysis, lipemia and icterus. The two most common outcomes of delta check alerts were ‘no problems found, standard report issued’ and ‘no problems found, report issued with comment’.
Conclusions
This study was the first nationwide survey of delta checks in China, the results of which help us to understand the current situation of delta checks in Chinese clinical laboratories.
Acknowledgments
We would like to extend our gratitude to the clinical laboratories in China that have taken part in our study and provided the relevant data that we needed. We are also deeply indebted to all the technical staff of the Clinet website (www.clinet.com.cn) for the technical support they provided.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: 1. National Natural Science Foundation of China (Funder Id: http://dx.doi.org/10.13039/ 501100001809, Grant No. 81871737). 2. Zhejiang Provincial Project for Medical and Health Science and Technology (Grant No. 2018KY009).
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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©2020 Walter de Gruyter GmbH, Berlin/Boston
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Artikel in diesem Heft
- Frontmatter
- Editorial
- New insights on the analytical performances for detecting and quantifying monoclonal proteins
- Reviews
- Vitamin C measurement in critical illness: challenges, methodologies and quality improvements
- Early predictors of perinatal brain damage: the role of neurobiomarkers
- Opinion Paper – Point
- Mixing studies for lupus anticoagulant: mostly yes, sometimes no
- Opinion Paper – Counterpoint
- Mixing studies for lupus anticoagulant: mostly no, sometimes yes
- EFLM Consensus Paper
- Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM
- Guidelines and Recommendations
- PREDICT: a checklist for preventing preanalytical diagnostic errors in clinical trials
- Genetics and Molecular Diagnostics
- Plasma vs. serum in circulating tumor DNA measurement: characterization by DNA fragment sizing and digital droplet polymerase chain reaction
- General Clinical Chemistry and Laboratory Medicine
- An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part I: factors impacting limit of quantitation of serum protein electrophoresis
- An international multi-center serum protein electrophoresis accuracy and M-protein isotyping study. Part II: limit of detection and follow-up of patients with small M-proteins
- Use of clinical data and acceleration profiles to validate pneumatic transportation systems
- National survey on delta checks in clinical laboratories in China
- Assessment of the glomerular filtration rate (GFR) in kidney transplant recipients using Bayesian estimation of the iohexol clearance
- Performance of Afinion HbA1c measurements in general practice as judged by external quality assurance data
- Renal tubular epithelial cells add value in the diagnosis of upper urinary tract pathology
- Reference Values and Biological Variations
- Influence of ethnicity on biochemical markers of health and disease in the CALIPER cohort of healthy children and adolescents
- Cardiovascular Diseases
- Clinical evaluation of capillary B-type natriuretic peptide testing
- Infectious Diseases
- Thrombo-inflammatory prognostic score improves qSOFA for risk stratification in patients with sepsis: a retrospective cohort study
- Corrigendum
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- Letters to the Editor
- Potential risks in fecal microbiota transplantation
- Macro-aspartate aminotransferase syndrome: a case report
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