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Elimination of Serum Complexed Prostate-Specific Antigen after Radical Retropubic Prostatectomy
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Carsten Stephan
Veröffentlicht/Copyright:
1. Juni 2005
Abstract
Total prostate-specific antigen (PSA) and complexed PSA were determined in venous blood from 12 patients with prostate cancer before and after radical prostatectomy by using Immuno 1 PSA assays. The elimination kinetics of complexed PSA were compared with that of total PSA. Nearly constant concentrations of complexed PSA were found during the first six hours after surgery, in contrast to the rapid elimination of free PSA and the significant decrease of total PSA. From day one to ten there was a continuous and nearly identical decrease of complexed PSA compared to total PSA. Our findings suggest that the initial rapid decrease of free PSA immediately after operation could be caused by formation of new PSA-complex.
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Published Online: 2005-06-01
Published in Print: 2000-04-30
Copyright © 2000 by Walter de Gruyter GmbH & Co. KG
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Artikel in diesem Heft
- The Clinical Usefulness of the Measurement of Cytokines
- Measurement of Cholesterol and other Lipoprotein Constituents in the Clinical Laboratory
- Serum ras (p21) as a Marker for Occupationally Derived Lung Cancer?
- Macro Lactate Dehydrogenase in a Patient with Myocarditis
- Elimination of Serum Complexed Prostate-Specific Antigen after Radical Retropubic Prostatectomy
- Suitability of Collection Tubes with Separator Gels for Collecting and Storing Blood Samples for Therapeutic Drug Monitoring (TDM)
- Influence of in vivo Hemoglobin Carbamylation on HbA1c Measurements by Various Methods
- Comparison of the Abbott IMx® and a High-Performance Liquid Chromatography Method for Measuring Total Plasma Homocysteine
- Evaluation of the ADVIA® Centaur™ TSH-3 Assay
- Biochemical Composition and Electrolyte Balance of "Unstimulated" Whole Human Saliva
- Evaluation of a New Simple and Rapid Enzyme-Linked Immunosorbent Assay Kit for Neopterin Determination
- Analytical and Clinical Evaluation of Troponin I Determination on Dimension RXL-HM
- Use of Ion-Selective Electrodes for Blood-Electrolyte Analysis. Recommendations for Nomenclature, Definitions and Conventions
- FESCC Survey on Accreditation and Post-Graduate Training in Clinical Chemistry in European Countries
- Clinical Use of Soluble Transferrin Receptor
- Macro Creatine Kinase Type 1: a Clinically Significant Marker?
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- The Bone and Mineral Manual – a Practical Guide. By Michael Kleerekoper, Ethel Sins, Michael McClung, editors
