Startseite Chapter 8 Biocatalytic applications of autotrophic organisms
Kapitel
Lizenziert
Nicht lizenziert Erfordert eine Authentifizierung

Chapter 8 Biocatalytic applications of autotrophic organisms

  • Hanna C. Grimm , Elif Erdem und Robert Kourist
Veröffentlichen auch Sie bei De Gruyter Brill
The Autotrophic Biorefinery
Ein Kapitel aus dem Buch The Autotrophic Biorefinery

Abstract

The autotrophic metabolism enables the fixation of inorganic carbon using energy sources such as light or reduced molecules from the environment. Whole-cell biotransformations in autotrophic cells use these energy modules for the sustainable regeneration of redox cofactors to drive enzymatic redox reactions. While reactions in wild-type hosts target oxidoreductases from the natural enzyme pool, genetic modification of cells allows the production of desired enzymes from different origins. The strategy circumvents disadvantages of traditional recycling systems such as a low atom efficiency and the requirement of sacrificial cosubstrates and paves the way for sustainable future biocatalysis to produce fine chemicals.

Abstract

The autotrophic metabolism enables the fixation of inorganic carbon using energy sources such as light or reduced molecules from the environment. Whole-cell biotransformations in autotrophic cells use these energy modules for the sustainable regeneration of redox cofactors to drive enzymatic redox reactions. While reactions in wild-type hosts target oxidoreductases from the natural enzyme pool, genetic modification of cells allows the production of desired enzymes from different origins. The strategy circumvents disadvantages of traditional recycling systems such as a low atom efficiency and the requirement of sacrificial cosubstrates and paves the way for sustainable future biocatalysis to produce fine chemicals.

Heruntergeladen am 2.11.2025 von https://www.degruyterbrill.com/document/doi/10.1515/9783110550603-008/html
Button zum nach oben scrollen